tetano
Editor, Senior Moderator
Am J Med Sci
. 2021 Jun 20;S0002-9629(21)00238-X.
doi: 10.1016/j.amjms.2021.06.007. Online ahead of print.
Splenic Infarction with Aortic Thrombosis in COVID-19
Jaques Sztajnbok[SUP] 1 [/SUP], Lucas Mendes Cunha de Resende Brasil[SUP] 2 [/SUP], Luis Arancibia Romero[SUP] 3 [/SUP], Ana Freitas Ribeiro[SUP] 4 [/SUP], Jose Ernesto Vidal[SUP] 5 [/SUP], Claudia Figueiredo-Melo[SUP] 6 [/SUP], Ceila Maria Sant'Ana Malaque[SUP] 7 [/SUP]
Affiliations
Abstract
Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19.
Keywords: Aorta; Covid-19; Spleen; Splenic infarction; Thrombosis.
. 2021 Jun 20;S0002-9629(21)00238-X.
doi: 10.1016/j.amjms.2021.06.007. Online ahead of print.
Splenic Infarction with Aortic Thrombosis in COVID-19
Jaques Sztajnbok[SUP] 1 [/SUP], Lucas Mendes Cunha de Resende Brasil[SUP] 2 [/SUP], Luis Arancibia Romero[SUP] 3 [/SUP], Ana Freitas Ribeiro[SUP] 4 [/SUP], Jose Ernesto Vidal[SUP] 5 [/SUP], Claudia Figueiredo-Melo[SUP] 6 [/SUP], Ceila Maria Sant'Ana Malaque[SUP] 7 [/SUP]
Affiliations
- PMID: 34161825
- DOI: 10.1016/j.amjms.2021.06.007
Abstract
Coronavirus disease 2019 (COVID-19) has been associated with an increased risk of venous and arterial thrombotic disease. Although pulmonary embolism has been the most common thrombotic complication, there have been recent reports of COVID-19-associated large-vessel ischemic stroke, acute upper- and lower-limb ischemia, as well as infarctions of the abdominal viscera, including renal, splenic, and small bowel infarctions. Here, we describe a case of splenic infarction (SI) associated with aortic thrombosis, which evolved despite the prophylactic use of low-molecular-weight heparin (LMWH), in a 60-year-old female patient with COVID-19. The patient was treated clinically with a therapeutic dose of LMWH, followed by warfarin, and eventually presented a favorable outcome. We also present a review of the literature regarding SI in patients with COVID-19.
Keywords: Aorta; Covid-19; Spleen; Splenic infarction; Thrombosis.