tetano
Editor, Senior Moderator
Am J Ophthalmol Case Rep
. 2022 Mar;25:101327.
doi: 10.1016/j.ajoc.2022.101327. Epub 2022 Jan 29.
Late retinal and optic nerve vascular complications due to COVID-19 in young individuals
Jaime Larrea[SUP] 1 [/SUP], Eva Villota-Deleu[SUP] 1 [/SUP], Beatriz Fernández-Vega[SUP] 1 [/SUP], Álvaro Fernández-Vega Sanz[SUP] 1 [/SUP]
Affiliations
Abstract
Purpose: This study aims to describe the late retinal and optic nerve vascular complications due Coronavirus disease 2019 (COVID-19) in a Spanish young population.
Methods: We describe 15 eyes of 15 young patients without any other systemic risk factors, except controlled arterial hypertension in 5 of them, with the diagnosis of Central retinal vein occlusion (CRVO), Branch retinal vein occlusion (BRVO), Central retinal artery occlusion (CRAO), Branch retinal artery occlusion (BRAO), Mixed occlusions (Artery and Vein) and Non-arteritic ischemic optic neuropathy (NAION) with a previous COVID-19 infection demonstrated with a positive COVID-19 IgG Test (COVID-19 IgG/IgM Rapid Test Cassette, Lambra Laboratories, Madrid, Spain.
Results: 9 males and 6 females, with a mean age of presentation of 49.7 ± 9 years old were included. The mean time between infection and diagnosis of the disease was 3.5 ± 1.2 months. The most common retinal or optic nerve vascular complication was CRVO (6 cases), following by CRAO (4 cases), Mixed arterial and venous occlusions (2 cases), NAION (2 cases) and BRAO (1 case).
Conclusions: The presence of a retinal or optic nerve vascular event in a young patient without any other hypercoagulable or genetic thrombophilic disorder, should make us rule out a previous COVID-19 infection. Ophthalmologists must be awared that retinal circulation could be another potential site for thromboembolic and optic nerve circulatory insufficiency complications of COVID-19. To our knowledge, this is the longest case series of retinal or optic nerve vascular events described after COVID-19 infection.
Keywords: COVID-19; Hypercoagulable state; Optic neuropathy; Retinal vascular occlusion.
. 2022 Mar;25:101327.
doi: 10.1016/j.ajoc.2022.101327. Epub 2022 Jan 29.
Late retinal and optic nerve vascular complications due to COVID-19 in young individuals
Jaime Larrea[SUP] 1 [/SUP], Eva Villota-Deleu[SUP] 1 [/SUP], Beatriz Fernández-Vega[SUP] 1 [/SUP], Álvaro Fernández-Vega Sanz[SUP] 1 [/SUP]
Affiliations
- PMID: 35128164
- PMCID: PMC8800541
- DOI: 10.1016/j.ajoc.2022.101327
Abstract
Purpose: This study aims to describe the late retinal and optic nerve vascular complications due Coronavirus disease 2019 (COVID-19) in a Spanish young population.
Methods: We describe 15 eyes of 15 young patients without any other systemic risk factors, except controlled arterial hypertension in 5 of them, with the diagnosis of Central retinal vein occlusion (CRVO), Branch retinal vein occlusion (BRVO), Central retinal artery occlusion (CRAO), Branch retinal artery occlusion (BRAO), Mixed occlusions (Artery and Vein) and Non-arteritic ischemic optic neuropathy (NAION) with a previous COVID-19 infection demonstrated with a positive COVID-19 IgG Test (COVID-19 IgG/IgM Rapid Test Cassette, Lambra Laboratories, Madrid, Spain.
Results: 9 males and 6 females, with a mean age of presentation of 49.7 ± 9 years old were included. The mean time between infection and diagnosis of the disease was 3.5 ± 1.2 months. The most common retinal or optic nerve vascular complication was CRVO (6 cases), following by CRAO (4 cases), Mixed arterial and venous occlusions (2 cases), NAION (2 cases) and BRAO (1 case).
Conclusions: The presence of a retinal or optic nerve vascular event in a young patient without any other hypercoagulable or genetic thrombophilic disorder, should make us rule out a previous COVID-19 infection. Ophthalmologists must be awared that retinal circulation could be another potential site for thromboembolic and optic nerve circulatory insufficiency complications of COVID-19. To our knowledge, this is the longest case series of retinal or optic nerve vascular events described after COVID-19 infection.
Keywords: COVID-19; Hypercoagulable state; Optic neuropathy; Retinal vascular occlusion.