tetano
Editor, Senior Moderator
Am J Perinatol
. 2023 Oct 10.
doi: 10.1055/a-2188-8511. Online ahead of print. Acceptance of routine vaccines in pregnancy during the COVID-19 pandemic
Allison Perelman[SUP] 1 [/SUP], Megan E Trostle[SUP] 2 [/SUP], Jillian Pecoriello[SUP] 1 [/SUP], Gwendolyn P Quinn[SUP] 1 [/SUP], Ashley Roman[SUP] 2 [/SUP], Christina A Penfield[SUP] 2 [/SUP]
Affiliations
Objective: Evaluate rates of vaccination against infectious diseases (Tdap and influenza) in pregnancy during the COVID-19 pandemic compared to contemporary historical controls.
Study design: This was a retrospective cohort study comparing rates of Tdap and influenza vaccination in pregnant people who received care at NYU Langone Health and delivered from 9/1/2020 to 1/1/2021 ("COVID cohort") to the same period the prior year ("2019 cohort"). Demographic information, trimester of initiation of prenatal care, insurance status, and medical comorbidities were evaluated. Outcomes were analyzed using Chi- squared, Fisher's exact test, and multivariable logistic regression, with significance of p<0.05.
Results: 1713 pregnant people were included. Compared to historical controls, the COVID cohort differed in age, race, timing of initiation of prenatal care, insurance status, and medical comorbidities. After adjusting for these covariates, pregnant people were significantly more likely to accept influenza vaccine in the COVID cohort (aOR 1.7, 95% CI 1.27-2.29) and had similar Tdap acceptance (aOR 1.5, 95% CI 0.99 - 2.17). However, this trend was not observed for the entire obstetric population; public insurance status and medical comorbidities were associated with lower vaccine rates during the pandemic. For those who had public insurance, rates of influenza vaccination decreased from 83% in 2019 to 40% during COVID (aOR 0.16, 95% CI 0.10 - 0.24) and for Tdap rates decreased from 93% to 54% (aOR 0.13, 95% CI 0.08 - 0.21).
Conclusion: During the COVID-19 pandemic era, pregnant people at large were more likely to accept the influenza vaccine. However, this trend did not apply to Tdap, and did not apply to high-risk groups with public insurance and medical comorbidities. This study highlights potential disparities in vaccination rates, which need to be accounted for when evaluating national vaccine trends. These data support increased efforts in vaccine counseling for high-risk populations.
. 2023 Oct 10.
doi: 10.1055/a-2188-8511. Online ahead of print. Acceptance of routine vaccines in pregnancy during the COVID-19 pandemic
Allison Perelman[SUP] 1 [/SUP], Megan E Trostle[SUP] 2 [/SUP], Jillian Pecoriello[SUP] 1 [/SUP], Gwendolyn P Quinn[SUP] 1 [/SUP], Ashley Roman[SUP] 2 [/SUP], Christina A Penfield[SUP] 2 [/SUP]
Affiliations
- PMID: 37816391
- DOI: 10.1055/a-2188-8511
Objective: Evaluate rates of vaccination against infectious diseases (Tdap and influenza) in pregnancy during the COVID-19 pandemic compared to contemporary historical controls.
Study design: This was a retrospective cohort study comparing rates of Tdap and influenza vaccination in pregnant people who received care at NYU Langone Health and delivered from 9/1/2020 to 1/1/2021 ("COVID cohort") to the same period the prior year ("2019 cohort"). Demographic information, trimester of initiation of prenatal care, insurance status, and medical comorbidities were evaluated. Outcomes were analyzed using Chi- squared, Fisher's exact test, and multivariable logistic regression, with significance of p<0.05.
Results: 1713 pregnant people were included. Compared to historical controls, the COVID cohort differed in age, race, timing of initiation of prenatal care, insurance status, and medical comorbidities. After adjusting for these covariates, pregnant people were significantly more likely to accept influenza vaccine in the COVID cohort (aOR 1.7, 95% CI 1.27-2.29) and had similar Tdap acceptance (aOR 1.5, 95% CI 0.99 - 2.17). However, this trend was not observed for the entire obstetric population; public insurance status and medical comorbidities were associated with lower vaccine rates during the pandemic. For those who had public insurance, rates of influenza vaccination decreased from 83% in 2019 to 40% during COVID (aOR 0.16, 95% CI 0.10 - 0.24) and for Tdap rates decreased from 93% to 54% (aOR 0.13, 95% CI 0.08 - 0.21).
Conclusion: During the COVID-19 pandemic era, pregnant people at large were more likely to accept the influenza vaccine. However, this trend did not apply to Tdap, and did not apply to high-risk groups with public insurance and medical comorbidities. This study highlights potential disparities in vaccination rates, which need to be accounted for when evaluating national vaccine trends. These data support increased efforts in vaccine counseling for high-risk populations.