tetano
Editor, Senior Moderator
Am J Perinatol
. 2022 Mar 3.
doi: 10.1055/a-1787-3673. Online ahead of print.
Characteristics and outcomes of pregnant women with and without Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in New York City: a matched cohort study
Rasha S Khoury[SUP] 1 [/SUP], Melissa Fazzari[SUP] 2 [/SUP], Calvin Lambert[SUP] 1 [/SUP], Chelsea Ann DeBolt[SUP] 3 [/SUP], Joanne Stone[SUP] 4 [/SUP], Angela T Bianco[SUP] 5 [/SUP], Lisa M Nathan[SUP] 6 [/SUP], Siobhan Dolan[SUP] 7 [/SUP], Peter S Bernstein[SUP] 8 [/SUP]
Affiliations
Abstract
Objective To examine the association between SARS-CoV-2 infection and preterm birth, cesarean birth and composite severe maternal morbidity by studying women with and without SARS-CoV-2 infection at time of delivery hospitalization from similar residential catchment areas in New York City. Methods A retrospective cohort study of pregnant women with laboratory-confirmed or denied SARS-CoV-2 on nasopharyngeal swab under universal testing policies at time of admission who gave birth between March 13 and May 15, 2020 at two New York City medical centers. Demographic and clinical data were collected and follow up was completed May 30, 2020. Groups were compared for the primary outcome, preterm birth, in adjusted (for age, race/ethnicity, nulliparity, Body Mass Index) and unadjusted analyses. Results Among this age matched cohort 164 women were positive and 247 were negative for SARS-CoV-2. Of the positive group 52.4% were asymptomatic and 1.2% had critical COVID-19. The groups did not differ by race and ethnicity, Body Mass Index, acute or chronic co-morbidities. Women with SARS-CoV-2 were more likely to be publicly insured. Preterm birth, cesarean birth and severe maternal morbidity did not differ between groups. Babies born to women with SARS-CoV-2 were more likely to have complications of prematurity or low birth weight (7.7% vs. 2%, p 0.01) Conclusion Preterm and cesarean birth did not differ between women with and without SARS-CoV-2 across disease severity in adjusted and unadjusted analysis among this cohort during the pandemic peak in New York City.
. 2022 Mar 3.
doi: 10.1055/a-1787-3673. Online ahead of print.
Characteristics and outcomes of pregnant women with and without Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) in New York City: a matched cohort study
Rasha S Khoury[SUP] 1 [/SUP], Melissa Fazzari[SUP] 2 [/SUP], Calvin Lambert[SUP] 1 [/SUP], Chelsea Ann DeBolt[SUP] 3 [/SUP], Joanne Stone[SUP] 4 [/SUP], Angela T Bianco[SUP] 5 [/SUP], Lisa M Nathan[SUP] 6 [/SUP], Siobhan Dolan[SUP] 7 [/SUP], Peter S Bernstein[SUP] 8 [/SUP]
Affiliations
- PMID: 35240711
- DOI: 10.1055/a-1787-3673
Abstract
Objective To examine the association between SARS-CoV-2 infection and preterm birth, cesarean birth and composite severe maternal morbidity by studying women with and without SARS-CoV-2 infection at time of delivery hospitalization from similar residential catchment areas in New York City. Methods A retrospective cohort study of pregnant women with laboratory-confirmed or denied SARS-CoV-2 on nasopharyngeal swab under universal testing policies at time of admission who gave birth between March 13 and May 15, 2020 at two New York City medical centers. Demographic and clinical data were collected and follow up was completed May 30, 2020. Groups were compared for the primary outcome, preterm birth, in adjusted (for age, race/ethnicity, nulliparity, Body Mass Index) and unadjusted analyses. Results Among this age matched cohort 164 women were positive and 247 were negative for SARS-CoV-2. Of the positive group 52.4% were asymptomatic and 1.2% had critical COVID-19. The groups did not differ by race and ethnicity, Body Mass Index, acute or chronic co-morbidities. Women with SARS-CoV-2 were more likely to be publicly insured. Preterm birth, cesarean birth and severe maternal morbidity did not differ between groups. Babies born to women with SARS-CoV-2 were more likely to have complications of prematurity or low birth weight (7.7% vs. 2%, p 0.01) Conclusion Preterm and cesarean birth did not differ between women with and without SARS-CoV-2 across disease severity in adjusted and unadjusted analysis among this cohort during the pandemic peak in New York City.