tetano
Editor, Senior Moderator
Am J Public Health
. 2021 Feb 18;e1-e4.
doi: 10.2105/AJPH.2020.306115. Online ahead of print.
Seroprevalence of SARS-CoV-2 Antibodies in Rhode Island From a Statewide Random Sample
Philip A Chan[SUP] 1 [/SUP], Ewa King[SUP] 1 [/SUP], Yizhen Xu[SUP] 1 [/SUP], William Goedel[SUP] 1 [/SUP], Leanne Lasher[SUP] 1 [/SUP], Matt Vargas[SUP] 1 [/SUP], Ken Brindamour[SUP] 1 [/SUP], Richard Huard[SUP] 1 [/SUP], Ailis Clyne[SUP] 1 [/SUP], James McDonald[SUP] 1 [/SUP], Utpala Bandy[SUP] 1 [/SUP], David Yokum[SUP] 1 [/SUP], Michelle L Rogers[SUP] 1 [/SUP], Laura Chambers[SUP] 1 [/SUP], Siena C Napoleon[SUP] 1 [/SUP], Nicole Alexander-Scott[SUP] 1 [/SUP], Joseph W Hogan[SUP] 1 [/SUP]
Affiliations
Abstract
Objectives. To characterize statewide seroprevalence and point prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Rhode Island.Methods. We conducted a cross-sectional survey of randomly selected households across Rhode Island in May 2020. Antibody-based and polymerase chain reaction (PCR)-based tests for SARS-CoV-2 were offered. Hispanics/Latinos and African Americans/Blacks were oversampled to ensure adequate representation. Seroprevalence estimations accounted for test sensitivity and specificity and were compared according to age, race/ethnicity, gender, housing environment, and transportation mode.Results. Overall, 1043 individuals from 554 households were tested (1032 antibody tests, 988 PCR tests). The estimated seroprevalence of SARS-CoV-2 antibodies was 2.1% (95% credible interval [CI] = 0.6, 4.1). Seroprevalence was 7.5% (95% CI = 1.3, 17.5) among Hispanics/Latinos, 3.8% (95% CI = 0.0, 15.0) among African Americans/Blacks, and 0.8% (95% CI = 0.0, 2.4) among non-Hispanic Whites. Overall PCR-based prevalence was 1.5% (95% CI = 0.5, 3.1).Conclusions. Rhode Island had low seroprevalence relative to other settings, but seroprevalence was substantially higher among African Americans/Blacks and Hispanics/Latinos. Rhode Island sits along the highly populated northeast corridor, making our findings broadly relevant to this region of the country. Continued monitoring via population-based sampling is needed to quantify these impacts going forward. (Am J Public Health. Published online ahead of print February 18, 2021: e1-e4. https://doi.org/10.2105/AJPH.2020.306115).
. 2021 Feb 18;e1-e4.
doi: 10.2105/AJPH.2020.306115. Online ahead of print.
Seroprevalence of SARS-CoV-2 Antibodies in Rhode Island From a Statewide Random Sample
Philip A Chan[SUP] 1 [/SUP], Ewa King[SUP] 1 [/SUP], Yizhen Xu[SUP] 1 [/SUP], William Goedel[SUP] 1 [/SUP], Leanne Lasher[SUP] 1 [/SUP], Matt Vargas[SUP] 1 [/SUP], Ken Brindamour[SUP] 1 [/SUP], Richard Huard[SUP] 1 [/SUP], Ailis Clyne[SUP] 1 [/SUP], James McDonald[SUP] 1 [/SUP], Utpala Bandy[SUP] 1 [/SUP], David Yokum[SUP] 1 [/SUP], Michelle L Rogers[SUP] 1 [/SUP], Laura Chambers[SUP] 1 [/SUP], Siena C Napoleon[SUP] 1 [/SUP], Nicole Alexander-Scott[SUP] 1 [/SUP], Joseph W Hogan[SUP] 1 [/SUP]
Affiliations
- PMID: 33600249
- DOI: 10.2105/AJPH.2020.306115
Abstract
Objectives. To characterize statewide seroprevalence and point prevalence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in Rhode Island.Methods. We conducted a cross-sectional survey of randomly selected households across Rhode Island in May 2020. Antibody-based and polymerase chain reaction (PCR)-based tests for SARS-CoV-2 were offered. Hispanics/Latinos and African Americans/Blacks were oversampled to ensure adequate representation. Seroprevalence estimations accounted for test sensitivity and specificity and were compared according to age, race/ethnicity, gender, housing environment, and transportation mode.Results. Overall, 1043 individuals from 554 households were tested (1032 antibody tests, 988 PCR tests). The estimated seroprevalence of SARS-CoV-2 antibodies was 2.1% (95% credible interval [CI] = 0.6, 4.1). Seroprevalence was 7.5% (95% CI = 1.3, 17.5) among Hispanics/Latinos, 3.8% (95% CI = 0.0, 15.0) among African Americans/Blacks, and 0.8% (95% CI = 0.0, 2.4) among non-Hispanic Whites. Overall PCR-based prevalence was 1.5% (95% CI = 0.5, 3.1).Conclusions. Rhode Island had low seroprevalence relative to other settings, but seroprevalence was substantially higher among African Americans/Blacks and Hispanics/Latinos. Rhode Island sits along the highly populated northeast corridor, making our findings broadly relevant to this region of the country. Continued monitoring via population-based sampling is needed to quantify these impacts going forward. (Am J Public Health. Published online ahead of print February 18, 2021: e1-e4. https://doi.org/10.2105/AJPH.2020.306115).