tetano
Editor, Senior Moderator
Am J Trop Med Hyg
. 2020 Sep 10.
doi: 10.4269/ajtmh.20-0869. Online ahead of print.
Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis
Aveek Mukherjee[SUP] 1 [/SUP], Raisa Ghosh[SUP] 1 [/SUP], Marlene Marte Furment[SUP] 1 [/SUP]
Affiliations
Abstract
Following its discovery in Wuhan, China, in December 2019, COVID-19 has attained pandemic status in mere months. It is caused by SARS-CoV-2, an enveloped beta coronavirus. This infection causes a prothrombogenic state by interplay of inflammatory mediators, and endothelial, microvascular, and possible hepatic damage and tissue tropism of the virus. This leads to frequent pulmonary and cerebral thromboembolism as well as occasional involvement of other organs. We present a 71-year-old man who initially presented with 2 weeks of fever, cough, and shortness of breath and was diagnosed with COVID-19 pneumonia. He required readmission due to worsened hypoxia and was later found to have left renal artery thrombosis with left kidney infarction, associated with an ascending aortic thrombus. He was anticoagulated and recovered uneventfully. We suggest that physicians have a high degree of suspicion to diagnose and manage the novel manifestations of this disease.
. 2020 Sep 10.
doi: 10.4269/ajtmh.20-0869. Online ahead of print.
Case Report: COVID-19 Associated Renal Infarction and Ascending Aortic Thrombosis
Aveek Mukherjee[SUP] 1 [/SUP], Raisa Ghosh[SUP] 1 [/SUP], Marlene Marte Furment[SUP] 1 [/SUP]
Affiliations
- PMID: 32918409
- DOI: 10.4269/ajtmh.20-0869
Abstract
Following its discovery in Wuhan, China, in December 2019, COVID-19 has attained pandemic status in mere months. It is caused by SARS-CoV-2, an enveloped beta coronavirus. This infection causes a prothrombogenic state by interplay of inflammatory mediators, and endothelial, microvascular, and possible hepatic damage and tissue tropism of the virus. This leads to frequent pulmonary and cerebral thromboembolism as well as occasional involvement of other organs. We present a 71-year-old man who initially presented with 2 weeks of fever, cough, and shortness of breath and was diagnosed with COVID-19 pneumonia. He required readmission due to worsened hypoxia and was later found to have left renal artery thrombosis with left kidney infarction, associated with an ascending aortic thrombus. He was anticoagulated and recovered uneventfully. We suggest that physicians have a high degree of suspicion to diagnose and manage the novel manifestations of this disease.