tetano
Editor, Senior Moderator
Am Surg
. 2023 May 4;31348231173976.
doi: 10.1177/00031348231173976. Online ahead of print. Colonic Perforation Secondary to COVID-19 Induced Hemorrhagic Colitis in a Patient Heterozygous for Factor V Leiden
Nicole Gherlone[SUP] 1 [/SUP], Priya Bhakta[SUP] 2 [/SUP], Marsha Apushkin[SUP] 3 [/SUP], Richard Zhu[SUP] 1 4 [/SUP]
Affiliations
Up to 17.6% of COVID-19 positive patients present with gastrointestinal symptoms and bowel wall abnormalities have been described in up to 31% of COVID-19 positive patients. Here, we present a case of a 40-year-old male diagnosed with COVID-19 complicated by hemorrhagic colitis leading to colonic perforation. CT scan of abdomen and pelvis demonstrated markedly distended descending and sigmoid colon with poorly defined wall, pneumatosis, and pneumoperitoneum. The patient was taken for emergent exploratory laparotomy for extended left hemicolectomy, partial omentectomy, transverse colostomy creation, abdominal washout, repair of small bowel, and appendectomy. The patient was brought back for repeat exploratory laparotomy with ICG perfusion assessment. Patient was found to be heterozygous for factor V Leiden mutation and was never vaccinated for COVID-19. Our case demonstrates a novel use for indocyanine green (ICG) to assess perfusion and underscores the importance of completing a thorough hypercoagulable evaluation following COVID-19 induced thrombotic event.
Keywords: COVID-19; colorectal; coronavirus; indocyanine green.
. 2023 May 4;31348231173976.
doi: 10.1177/00031348231173976. Online ahead of print. Colonic Perforation Secondary to COVID-19 Induced Hemorrhagic Colitis in a Patient Heterozygous for Factor V Leiden
Nicole Gherlone[SUP] 1 [/SUP], Priya Bhakta[SUP] 2 [/SUP], Marsha Apushkin[SUP] 3 [/SUP], Richard Zhu[SUP] 1 4 [/SUP]
Affiliations
- PMID: 37142231
- DOI: 10.1177/00031348231173976
Up to 17.6% of COVID-19 positive patients present with gastrointestinal symptoms and bowel wall abnormalities have been described in up to 31% of COVID-19 positive patients. Here, we present a case of a 40-year-old male diagnosed with COVID-19 complicated by hemorrhagic colitis leading to colonic perforation. CT scan of abdomen and pelvis demonstrated markedly distended descending and sigmoid colon with poorly defined wall, pneumatosis, and pneumoperitoneum. The patient was taken for emergent exploratory laparotomy for extended left hemicolectomy, partial omentectomy, transverse colostomy creation, abdominal washout, repair of small bowel, and appendectomy. The patient was brought back for repeat exploratory laparotomy with ICG perfusion assessment. Patient was found to be heterozygous for factor V Leiden mutation and was never vaccinated for COVID-19. Our case demonstrates a novel use for indocyanine green (ICG) to assess perfusion and underscores the importance of completing a thorough hypercoagulable evaluation following COVID-19 induced thrombotic event.
Keywords: COVID-19; colorectal; coronavirus; indocyanine green.