tetano
Editor, Senior Moderator
Avian Pathol. 2015 Feb 23:1-33. [Epub ahead of print]
[h=1]Analysis of signs and pathology of H5N1-infected ducks from 2010-2011 Korean highly pathogenic avian influenza outbreak suggests the influence of age and management practices on severity of disease.[/h] Rhyoo MY[SUP]1[/SUP], Lee KH, Moon OK, Park WH, Bae YC, Jung JY, Yoon SS, Kim HR, Lee MH, Lee EJ, Ki MR, Jeong KS.
[h=3]Author information[/h]
[h=3]Abstract[/h] We compared the clinical signs, histopathological lesions, and viral antigens distribution among the infected young (meat-type) and older (breeder) ducks that were naturally infected with the highly pathogenic avian influenza (HPAI) virus during the 2010-2011 Korean outbreak. The meat-type ducks had a high mortality rate (30%) and showed severe neurologic signs such as head tremors and paresis. In contrast, HPAI-infected breeder ducks had minimal clinical symptoms but a decreased egg production rate. The histopathological characteristics of infected meat-type ducks included necrotic lesions of heart and brain, which may have primarily contributed to the high mortality rate. In contrast, the breeder ducks only presented necrotic splenitis and viral antigens were only detected in the trachea, lungs and spleen. Younger ducks had a high viral titer in the organs, high levels of viral shedding, and a high mortality rate after experimental HPAI virus infection. Compared to the breeder ducks, the meat-type ducks were raised in smaller farms that had poor quarantine and breeding facilities. It is therefore possible that better biosecurity in the breeder farms could have reduced the infection dose and subsequently the severity of the disease. Thus, age and management may influencing factors for HPAI susceptibility in ducks.
PMID: 25703639 [PubMed - as supplied by publisher]
[h=1]Analysis of signs and pathology of H5N1-infected ducks from 2010-2011 Korean highly pathogenic avian influenza outbreak suggests the influence of age and management practices on severity of disease.[/h] Rhyoo MY[SUP]1[/SUP], Lee KH, Moon OK, Park WH, Bae YC, Jung JY, Yoon SS, Kim HR, Lee MH, Lee EJ, Ki MR, Jeong KS.
[h=3]Author information[/h]
[h=3]Abstract[/h] We compared the clinical signs, histopathological lesions, and viral antigens distribution among the infected young (meat-type) and older (breeder) ducks that were naturally infected with the highly pathogenic avian influenza (HPAI) virus during the 2010-2011 Korean outbreak. The meat-type ducks had a high mortality rate (30%) and showed severe neurologic signs such as head tremors and paresis. In contrast, HPAI-infected breeder ducks had minimal clinical symptoms but a decreased egg production rate. The histopathological characteristics of infected meat-type ducks included necrotic lesions of heart and brain, which may have primarily contributed to the high mortality rate. In contrast, the breeder ducks only presented necrotic splenitis and viral antigens were only detected in the trachea, lungs and spleen. Younger ducks had a high viral titer in the organs, high levels of viral shedding, and a high mortality rate after experimental HPAI virus infection. Compared to the breeder ducks, the meat-type ducks were raised in smaller farms that had poor quarantine and breeding facilities. It is therefore possible that better biosecurity in the breeder farms could have reduced the infection dose and subsequently the severity of the disease. Thus, age and management may influencing factors for HPAI susceptibility in ducks.
PMID: 25703639 [PubMed - as supplied by publisher]