tetano
Editor, Senior Moderator
Enferm Infecc Microbiol Clin. 2019 Oct 24. pii: S0213-005X(19)30233-2. doi: 10.1016/j.eimc.2019.08.008. [Epub ahead of print] [h=1]Analysis of the impact of diagnostic virology tests on the use of antibiotics in paediatric inpatients with community-acquired pneumonia.[/h]
[Article in English, Spanish]
Aguilera-Alonso D[SUP]1[/SUP], Ill?n-Ramos M[SUP]2[/SUP], Daoud Z[SUP]2[/SUP], Guinea V[SUP]2[/SUP], Culebras E[SUP]3[/SUP], Ramos JT[SUP]2[/SUP].
[h=3]Author information[/h] 1 Servicio de Pediatr?a, Hospital Cl?nico San Carlos, Madrid, Espa?a; Instituto de Investigaci?n Sanitaria, Hospital Cl?nico San Carlos, Madrid, Espa?a. Electronic address: david.aguilera@salud.madrid.org. 2 Servicio de Pediatr?a, Hospital Cl?nico San Carlos, Madrid, Espa?a; Instituto de Investigaci?n Sanitaria, Hospital Cl?nico San Carlos, Madrid, Espa?a. 3 Servicio de Microbiolog?a, Hospital Cl?nico San Carlos, Madrid, Espa?a.
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Viruses are one of the most common causes of community-acquired pneumonia (CAP) in children. Early identification of respiratory viruses could result in a decrease in the use of antibiotics.
[h=4]METHODS:[/h] Observational, retrospective study from January 2014 to June 2018, that included paediatric patients admitted with a diagnosis of CAP in a tertiary hospital, in which antigenic tests and/or viral PCR on a respiratory sample was performed.
[h=4]RESULTS:[/h] A total of 105 CAP episodes were included, with identification of a respiratory virus in 93 (88.6%) cases. Patients with respiratory syncytial virus (RSV) detection had a lower onset of empirical antibiotic therapy (35.1% vs. 55.9%, P-value=.042). In addition, cases with RSV or influenza identification required shorter duration of antibiotic therapy (receiving 45.6% ≥2 days vs. 68.8% of those not identified, P=.017).
[h=4]CONCLUSION:[/h] The use of respiratory virus diagnostic techniques in our setting can optimise antibiotic use in children admitted with CAP.
Copyright ? 2019 Elsevier Espa?a, S.L.U. and Sociedad Espa?ola de Enfermedades Infecciosas y Microbiolog?a Cl?nica. All rights reserved.
[h=4]KEYWORDS:[/h] Antimicrobial stewardship; Children; Neumon?a; Ni?os; Optimizaci?n de consumo de antibi?ticos; Paediatrics; Pediatr?a; Pneumonia; Respiratory virus testing; Test de virus respiratorios
PMID: 31668863 DOI: 10.1016/j.eimc.2019.08.008
[Article in English, Spanish]
Aguilera-Alonso D[SUP]1[/SUP], Ill?n-Ramos M[SUP]2[/SUP], Daoud Z[SUP]2[/SUP], Guinea V[SUP]2[/SUP], Culebras E[SUP]3[/SUP], Ramos JT[SUP]2[/SUP].
[h=3]Author information[/h] 1 Servicio de Pediatr?a, Hospital Cl?nico San Carlos, Madrid, Espa?a; Instituto de Investigaci?n Sanitaria, Hospital Cl?nico San Carlos, Madrid, Espa?a. Electronic address: david.aguilera@salud.madrid.org. 2 Servicio de Pediatr?a, Hospital Cl?nico San Carlos, Madrid, Espa?a; Instituto de Investigaci?n Sanitaria, Hospital Cl?nico San Carlos, Madrid, Espa?a. 3 Servicio de Microbiolog?a, Hospital Cl?nico San Carlos, Madrid, Espa?a.
[h=3]Abstract[/h] [h=4]INTRODUCTION:[/h] Viruses are one of the most common causes of community-acquired pneumonia (CAP) in children. Early identification of respiratory viruses could result in a decrease in the use of antibiotics.
[h=4]METHODS:[/h] Observational, retrospective study from January 2014 to June 2018, that included paediatric patients admitted with a diagnosis of CAP in a tertiary hospital, in which antigenic tests and/or viral PCR on a respiratory sample was performed.
[h=4]RESULTS:[/h] A total of 105 CAP episodes were included, with identification of a respiratory virus in 93 (88.6%) cases. Patients with respiratory syncytial virus (RSV) detection had a lower onset of empirical antibiotic therapy (35.1% vs. 55.9%, P-value=.042). In addition, cases with RSV or influenza identification required shorter duration of antibiotic therapy (receiving 45.6% ≥2 days vs. 68.8% of those not identified, P=.017).
[h=4]CONCLUSION:[/h] The use of respiratory virus diagnostic techniques in our setting can optimise antibiotic use in children admitted with CAP.
Copyright ? 2019 Elsevier Espa?a, S.L.U. and Sociedad Espa?ola de Enfermedades Infecciosas y Microbiolog?a Cl?nica. All rights reserved.
[h=4]KEYWORDS:[/h] Antimicrobial stewardship; Children; Neumon?a; Ni?os; Optimizaci?n de consumo de antibi?ticos; Paediatrics; Pediatr?a; Pneumonia; Respiratory virus testing; Test de virus respiratorios
PMID: 31668863 DOI: 10.1016/j.eimc.2019.08.008