tetano
Editor, Senior Moderator
Angiology
. 2022 Feb 6;33197211072346.
doi: 10.1177/00033197211072346. Online ahead of print.
Relationship Between Blood Lipid Levels and Mortality in Hospitalized COVID-19 Patients
Sidar Ş Aydın[SUP] 1 [/SUP], Emrah Aksakal[SUP] 2 [/SUP], Faruk Aydınyılmaz[SUP] 2 [/SUP], Oktay Gülcü[SUP] 2 [/SUP], İbrahim Saraç[SUP] 2 [/SUP], Kamuran Kalkan[SUP] 2 [/SUP], Selim Aydemir[SUP] 3 [/SUP], Remziye Doğan[SUP] 4 [/SUP], Uğur Aksu[SUP] 5 [/SUP], İbrahim H Tanboğa[SUP] 6 [/SUP]
Affiliations
Abstract
People with comorbid conditions are at increased risk of developing severe/fatal coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between lipid levels and mortality in patients hospitalized for COVID-19 infection. In this retrospective study, we collected the details of 5274 COVID-19 patients who were diagnosed using the polymerase chain reaction and/or computed tomography and were hospitalized between March and November 2020. Patients (n = 4118) whose blood lipid levels were checked within the first 24 h after hospitalization were included in the study. Multivariable cox proportional hazards regression was used to assess the relationship between lipid variables such as low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) and death. There was a statistically significant association between LDL-C, HDL-C, and TG levels and the risk of death (P =.002, <.001, and .035, respectively). Low and high LDL-C, low HDL-C, and high TG levels were negatively associated with COVID-19-related mortality. Blood lipid levels may be useful predictors of mortality in COVID-19 patients.
Keywords: COVID-19; SARS-CoV-2; lipid levels; mortality.
. 2022 Feb 6;33197211072346.
doi: 10.1177/00033197211072346. Online ahead of print.
Relationship Between Blood Lipid Levels and Mortality in Hospitalized COVID-19 Patients
Sidar Ş Aydın[SUP] 1 [/SUP], Emrah Aksakal[SUP] 2 [/SUP], Faruk Aydınyılmaz[SUP] 2 [/SUP], Oktay Gülcü[SUP] 2 [/SUP], İbrahim Saraç[SUP] 2 [/SUP], Kamuran Kalkan[SUP] 2 [/SUP], Selim Aydemir[SUP] 3 [/SUP], Remziye Doğan[SUP] 4 [/SUP], Uğur Aksu[SUP] 5 [/SUP], İbrahim H Tanboğa[SUP] 6 [/SUP]
Affiliations
- PMID: 35124978
- DOI: 10.1177/00033197211072346
Abstract
People with comorbid conditions are at increased risk of developing severe/fatal coronavirus disease 2019 (COVID-19). We aimed to investigate the relationship between lipid levels and mortality in patients hospitalized for COVID-19 infection. In this retrospective study, we collected the details of 5274 COVID-19 patients who were diagnosed using the polymerase chain reaction and/or computed tomography and were hospitalized between March and November 2020. Patients (n = 4118) whose blood lipid levels were checked within the first 24 h after hospitalization were included in the study. Multivariable cox proportional hazards regression was used to assess the relationship between lipid variables such as low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C) and triglycerides (TG) and death. There was a statistically significant association between LDL-C, HDL-C, and TG levels and the risk of death (P =.002, <.001, and .035, respectively). Low and high LDL-C, low HDL-C, and high TG levels were negatively associated with COVID-19-related mortality. Blood lipid levels may be useful predictors of mortality in COVID-19 patients.
Keywords: COVID-19; SARS-CoV-2; lipid levels; mortality.