tetano
Editor, Senior Moderator
Animals (Basel)
. 2021 Mar 2;11(3):667.
doi: 10.3390/ani11030667.
SARS-CoV-2 Seroprevalence in Household Domestic Ferrets ( Mustela putorius furo)
Jacobo Giner[SUP] 1 2 [/SUP], Sergio Villanueva-Saz[SUP] 3 4 5 [/SUP], Ana Pilar Tobajas[SUP] 5 6 [/SUP], Mar?a Dolores P?rez[SUP] 5 6 [/SUP], Ana Gonz?lez[SUP] 2 [/SUP], Maite Verde[SUP] 2 3 5 [/SUP], Andr?s Yzuel[SUP] 3 [/SUP], Ana Garc?a-Garc?a[SUP] 7 [/SUP], V?ctor Taleb[SUP] 7 [/SUP], Erandi Lira-Navarrete[SUP] 7 [/SUP], Ram?n Hurtado-Guerrero[SUP] 7 8 9 10 [/SUP], Juli?n Pardo[SUP] 8 11 12 [/SUP], Llipsy Santiago[SUP] 11 [/SUP], Jos? Ram?n Pa?o[SUP] 13 [/SUP], H?ctor Ru?z[SUP] 2 [/SUP], Delia Lacasta[SUP] 2 5 [/SUP], Antonio Fern?ndez[SUP] 2 3 5 [/SUP]
Affiliations
Abstract
Animal infections with SARS-CoV-2 have been reported in different countries and several animal species have been proven to be susceptible to infection with SARS-CoV-2 both naturally and by experimental infection. Moreover, infections under natural conditions in more than 20 mink farms have been reported where humans could have been the source of infection for minks. However, little information is available about the susceptibility of pet animals under natural conditions and currently there is no SARS-CoV-2 epidemiological assessment occurrence in household ferrets. In this study, the presence of SARS-CoV-2 antibodies was evaluated in serum samples obtained from 127 household ferrets (Mustela putorius furo) in the Province of Valencia (Spain). Two ferrets tested positive to SARS-CoV-2 (1.57%) by in-house enzyme-linked immunosorbent assay based on receptor binding domain (RBD) of Spike antigen. Furthermore, anti-RBD SARS-CoV-2 antibodies persisted at detectable levels in a seropositive SARS-CoV-2 domestic ferret beyond 129 days since the first time antibodies were detected. This study reports for the first time the evidence of household pet ferrets exposure to SARS-CoV-2 in Spain to date.
Keywords: ELISA; SARS-CoV-2; coronavirus disease 2019 (COVID-19); household ferrets; serology.
. 2021 Mar 2;11(3):667.
doi: 10.3390/ani11030667.
SARS-CoV-2 Seroprevalence in Household Domestic Ferrets ( Mustela putorius furo)
Jacobo Giner[SUP] 1 2 [/SUP], Sergio Villanueva-Saz[SUP] 3 4 5 [/SUP], Ana Pilar Tobajas[SUP] 5 6 [/SUP], Mar?a Dolores P?rez[SUP] 5 6 [/SUP], Ana Gonz?lez[SUP] 2 [/SUP], Maite Verde[SUP] 2 3 5 [/SUP], Andr?s Yzuel[SUP] 3 [/SUP], Ana Garc?a-Garc?a[SUP] 7 [/SUP], V?ctor Taleb[SUP] 7 [/SUP], Erandi Lira-Navarrete[SUP] 7 [/SUP], Ram?n Hurtado-Guerrero[SUP] 7 8 9 10 [/SUP], Juli?n Pardo[SUP] 8 11 12 [/SUP], Llipsy Santiago[SUP] 11 [/SUP], Jos? Ram?n Pa?o[SUP] 13 [/SUP], H?ctor Ru?z[SUP] 2 [/SUP], Delia Lacasta[SUP] 2 5 [/SUP], Antonio Fern?ndez[SUP] 2 3 5 [/SUP]
Affiliations
- PMID: 33801548
- DOI: 10.3390/ani11030667
Abstract
Animal infections with SARS-CoV-2 have been reported in different countries and several animal species have been proven to be susceptible to infection with SARS-CoV-2 both naturally and by experimental infection. Moreover, infections under natural conditions in more than 20 mink farms have been reported where humans could have been the source of infection for minks. However, little information is available about the susceptibility of pet animals under natural conditions and currently there is no SARS-CoV-2 epidemiological assessment occurrence in household ferrets. In this study, the presence of SARS-CoV-2 antibodies was evaluated in serum samples obtained from 127 household ferrets (Mustela putorius furo) in the Province of Valencia (Spain). Two ferrets tested positive to SARS-CoV-2 (1.57%) by in-house enzyme-linked immunosorbent assay based on receptor binding domain (RBD) of Spike antigen. Furthermore, anti-RBD SARS-CoV-2 antibodies persisted at detectable levels in a seropositive SARS-CoV-2 domestic ferret beyond 129 days since the first time antibodies were detected. This study reports for the first time the evidence of household pet ferrets exposure to SARS-CoV-2 in Spain to date.
Keywords: ELISA; SARS-CoV-2; coronavirus disease 2019 (COVID-19); household ferrets; serology.