tetano
Editor, Senior Moderator
Epidemiol Infect. 2014 Oct 15:1-11. [Epub ahead of print]
Antibody response and risk factors for seropositivity in backyard poultry following mass vaccination against highly pathogenic avian influenza and Newcastle disease in Indonesia.
McLAWS M1, Priyono W2, Bett B1, Al-Qamar S3, Claassen I4, Widiastuti T2, Poole J1, Schoonman L1, Jost C1, Mariner J1.
Author information
Abstract
SUMMARY A large-scale mass vaccination campaign was carried out in Java, Indonesia in an attempt to control outbreaks of highly pathogenic avian influenza (HPAI) in backyard flocks and commercial smallholder poultry. Sero-monitoring was conducted in mass vaccination and control areas to assess the proportion of the target population with antibodies against HPAI and Newcastle disease (ND). There were four rounds of vaccination, and samples were collected after each round resulting in a total of 27 293 samples. Sampling was performed irrespective of vaccination status. In the mass vaccination areas, 20-45% of poultry sampled had a positive titre to H5 after each round of vaccination, compared to 2-3% in the control group. In the HPAI + ND vaccination group, 12-25% of the population had positive ND titres, compared to 5-13% in the areas without ND vaccination. The level of seropositivity varied by district, age of the bird, and species (ducks vs. chickens).
PMID:
25316261
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25316261
Antibody response and risk factors for seropositivity in backyard poultry following mass vaccination against highly pathogenic avian influenza and Newcastle disease in Indonesia.
McLAWS M1, Priyono W2, Bett B1, Al-Qamar S3, Claassen I4, Widiastuti T2, Poole J1, Schoonman L1, Jost C1, Mariner J1.
Author information
Abstract
SUMMARY A large-scale mass vaccination campaign was carried out in Java, Indonesia in an attempt to control outbreaks of highly pathogenic avian influenza (HPAI) in backyard flocks and commercial smallholder poultry. Sero-monitoring was conducted in mass vaccination and control areas to assess the proportion of the target population with antibodies against HPAI and Newcastle disease (ND). There were four rounds of vaccination, and samples were collected after each round resulting in a total of 27 293 samples. Sampling was performed irrespective of vaccination status. In the mass vaccination areas, 20-45% of poultry sampled had a positive titre to H5 after each round of vaccination, compared to 2-3% in the control group. In the HPAI + ND vaccination group, 12-25% of the population had positive ND titres, compared to 5-13% in the areas without ND vaccination. The level of seropositivity varied by district, age of the bird, and species (ducks vs. chickens).
PMID:
25316261
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/25316261