Giuseppe
Emeritus
[Source: Antimicrobial Agents and Chemotherapy, full page: (LINK). Abstract, edited.]
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Comparative population analysis of Klebsiella pneumoniae with extended-spectrum β-lactamases colonizing patients in rehabilitation centers in four countries
A. Baraniak 1, R. Izdebski 1, J. Fiett 1, E. Sadowy 1, A. Adler 2, M. Kazma 2, J. Salomon 3, C. Lawrence 4, A. Rossini 5, A. Salvia 5, J. Vidal Samso 6, J. Fierro 6, M. Paul 7, Y. Lerman 8, S. Malhotra-Kumar 9, C. Lammens 9, H. Goossens 9, W. Hryniewicz 1, C. Brun-Buisson 10, Y. Carmeli 2 and M. Gniadkowski 1,* on behalf of the MOSAR WP2 & WP5 study groups
Author Affiliations: <SUP>1</SUP>National Medicines Institute, Warsaw, Poland <SUP>2</SUP>Division of Epidemiology and Preventive Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel <SUP>3</SUP>INSERM, MSRSS, Cnam, Paris, France <SUP>4</SUP>Groupe Hospitalier Universitaire Paris Ile-de-France Ouest, France <SUP>5</SUP>Fondazione Santa Lucia IRCCS, Rome, Italy <SUP>6</SUP>Institute Guttmann, Barcelona, Spain <SUP>7</SUP>Loewenstein Hospital, Ra?anana, Israel <SUP>8</SUP>Geriatric Division, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel <SUP></SUP>University of Antwerp, Antwerp, Belgium <SUP>10</SUP>INSERM, U957 & Universit? Paris-Est, Cr?teil, France
ABSTRACT
The international project MOSAR was conducted in five rehabilitation centers; patients were screened for rectal carriage of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. Among 229 Klebsiella pneumoniae isolates four clonal groups (CG) or complexes (CC) prevailed: CG17 in France, CG101 in Italy, CG15 in Spain, and CC147 in Israel. ESBLs, mainly CTX-Ms, were produced by 226 isolates; three isolates expressed AmpC-like cephalosporinases. High genetic diversity of K. pneumoniae populations was observed, with specific characteristics at each center.
FOOTNOTES
* Corresponding author: Marek Gniadkowski, National Medicines Institute, ul. Chełmska 30/34, 00-725 Warsaw, Poland. Fax: (+48) 22 - 841 29 49. E-mail: gniadkow@cls.edu.pl
Copyright ? 2013, American Society for Microbiology. All Rights Reserved.
-A. Baraniak 1, R. Izdebski 1, J. Fiett 1, E. Sadowy 1, A. Adler 2, M. Kazma 2, J. Salomon 3, C. Lawrence 4, A. Rossini 5, A. Salvia 5, J. Vidal Samso 6, J. Fierro 6, M. Paul 7, Y. Lerman 8, S. Malhotra-Kumar 9, C. Lammens 9, H. Goossens 9, W. Hryniewicz 1, C. Brun-Buisson 10, Y. Carmeli 2 and M. Gniadkowski 1,* on behalf of the MOSAR WP2 & WP5 study groups
Author Affiliations: <SUP>1</SUP>National Medicines Institute, Warsaw, Poland <SUP>2</SUP>Division of Epidemiology and Preventive Medicine, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel <SUP>3</SUP>INSERM, MSRSS, Cnam, Paris, France <SUP>4</SUP>Groupe Hospitalier Universitaire Paris Ile-de-France Ouest, France <SUP>5</SUP>Fondazione Santa Lucia IRCCS, Rome, Italy <SUP>6</SUP>Institute Guttmann, Barcelona, Spain <SUP>7</SUP>Loewenstein Hospital, Ra?anana, Israel <SUP>8</SUP>Geriatric Division, Tel-Aviv Sourasky Medical Center, Tel-Aviv, Israel <SUP></SUP>University of Antwerp, Antwerp, Belgium <SUP>10</SUP>INSERM, U957 & Universit? Paris-Est, Cr?teil, France
ABSTRACT
The international project MOSAR was conducted in five rehabilitation centers; patients were screened for rectal carriage of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. Among 229 Klebsiella pneumoniae isolates four clonal groups (CG) or complexes (CC) prevailed: CG17 in France, CG101 in Italy, CG15 in Spain, and CC147 in Israel. ESBLs, mainly CTX-Ms, were produced by 226 isolates; three isolates expressed AmpC-like cephalosporinases. High genetic diversity of K. pneumoniae populations was observed, with specific characteristics at each center.
FOOTNOTES
* Corresponding author: Marek Gniadkowski, National Medicines Institute, ul. Chełmska 30/34, 00-725 Warsaw, Poland. Fax: (+48) 22 - 841 29 49. E-mail: gniadkow@cls.edu.pl
Copyright ? 2013, American Society for Microbiology. All Rights Reserved.
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