Giuseppe
Emeritus
[Source: Antimicrobial Agents and Chemotherapy, full text: (LINK). Abstract, edited.]
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Dissemination of a Carbapenem Resistant Acinetobacter baumannii Strain Belonging to International Clone II/ST2 and Harbouring a Novel AbaR4-like Resistance Island in Latvia
Mara Saule 1,2, ?rjan Samuelsen 3,*, Uga Dumpis 1,2, Arnfinn Sundsfjord 3,4, Aija Karlsone 2, Arta Balode 1,5, Edvins Miklasevics 1,5 and Nabil Karah 3,4,*
Author Affiliations: <SUP>1</SUP>P. Stradins Clinical University Hospital; <SUP>2</SUP>University of Latvia; <SUP>5</SUP>Riga Stradins University; <SUP>3</SUP>Riga, Latvia, and Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway; <SUP>4</SUP>Research Group for Host-Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Troms?, Troms?, Norway
ABSTRACT
An outbreak of hospital-acquired A. baumannii infections, caused by a bla<SUB>OXA-23</SUB>-positive carbapenem resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and intI1-aacA4-catB8-aadA1-qacEΔ1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of ∼ 46500 bp containing structures similar to the previously described AbaR22 and Tn6167 islands. AbaR25 was characterized by the occurrence of a second copy of Tn6022a interrupted by Tn2006 carrying the bla<SUB>OXA-23</SUB> gene.
FOOTNOTES
*Corresponding authors. Mailing address: Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Sykehusveien 38, Troms? 9038, Norway. Phone: +47 99 261 822. Fax: +47 77 627 015. E-mail: nabil.karah@unn.no
*orjan.samuelsen@unn.no.
Copyright ? 2012, American Society for Microbiology. All Rights Reserved.
-Author Affiliations: <SUP>1</SUP>P. Stradins Clinical University Hospital; <SUP>2</SUP>University of Latvia; <SUP>5</SUP>Riga Stradins University; <SUP>3</SUP>Riga, Latvia, and Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway; <SUP>4</SUP>Research Group for Host-Microbe Interactions, Department of Medical Biology, Faculty of Health Sciences, University of Troms?, Troms?, Norway
ABSTRACT
An outbreak of hospital-acquired A. baumannii infections, caused by a bla<SUB>OXA-23</SUB>-positive carbapenem resistant strain belonging to international clone II/ST2, was detected in Latvia. The strain was partially equipped with the armA gene and intI1-aacA4-catB8-aadA1-qacEΔ1 class 1 integron. In addition, the strain carried AbaR25, a novel AbaR4-like resistance island of ∼ 46500 bp containing structures similar to the previously described AbaR22 and Tn6167 islands. AbaR25 was characterized by the occurrence of a second copy of Tn6022a interrupted by Tn2006 carrying the bla<SUB>OXA-23</SUB> gene.
FOOTNOTES
*Corresponding authors. Mailing address: Reference Centre for Detection of Antimicrobial Resistance, Department of Microbiology and Infection Control, University Hospital of North Norway, Sykehusveien 38, Troms? 9038, Norway. Phone: +47 99 261 822. Fax: +47 77 627 015. E-mail: nabil.karah@unn.no
*orjan.samuelsen@unn.no.
Copyright ? 2012, American Society for Microbiology. All Rights Reserved.
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