tetano
Editor, Senior Moderator
Antimicrob Agents Chemother
. 2021 Jan 25;AAC.02167-20.
doi: 10.1128/AAC.02167-20. Online ahead of print.
Limited Utility of Procalcitonin in Identifying Community-Associated Bacterial Infections in Patients Presenting with Coronavirus Disease 2019
Michael May[SUP] 1 [/SUP], Michelle Chang[SUP] 1 [/SUP], Donald Dietz[SUP] 2 [/SUP], Sherif Shoucri[SUP] 2 [/SUP], Justin Laracy[SUP] 2 [/SUP], Magdalena E Sobieszczyk[SUP] 2 [/SUP], Anne-Catrin Uhlemann[SUP] 2 [/SUP], Jason Zucker[SUP] 2 [/SUP], Christine J Kubin[SUP] 3 [/SUP]
Affiliations
Abstract
The role of procalcitonin in identifying community-associated bacterial infections among patients with coronavirus disease 2019 is not yet established. In 2443 patients with 148 bacterial co-infections, mean procalcitonin levels were significantly higher with any bacterial infection (13.16 ? 51.19 ng/mL, p=0.0091) and with bacteremia (34.25 ? 85.01 ng/mL, p=0.0125) than without infection (2.00 ?15.26 ng/mL). Procalcitonin (cutoff 0.25 or 0.50 ng/mL) did not reliably identify bacterial co-infections, but may be useful in excluding bacterial infection.
. 2021 Jan 25;AAC.02167-20.
doi: 10.1128/AAC.02167-20. Online ahead of print.
Limited Utility of Procalcitonin in Identifying Community-Associated Bacterial Infections in Patients Presenting with Coronavirus Disease 2019
Michael May[SUP] 1 [/SUP], Michelle Chang[SUP] 1 [/SUP], Donald Dietz[SUP] 2 [/SUP], Sherif Shoucri[SUP] 2 [/SUP], Justin Laracy[SUP] 2 [/SUP], Magdalena E Sobieszczyk[SUP] 2 [/SUP], Anne-Catrin Uhlemann[SUP] 2 [/SUP], Jason Zucker[SUP] 2 [/SUP], Christine J Kubin[SUP] 3 [/SUP]
Affiliations
- PMID: 33495224
- DOI: 10.1128/AAC.02167-20
Abstract
The role of procalcitonin in identifying community-associated bacterial infections among patients with coronavirus disease 2019 is not yet established. In 2443 patients with 148 bacterial co-infections, mean procalcitonin levels were significantly higher with any bacterial infection (13.16 ? 51.19 ng/mL, p=0.0091) and with bacteremia (34.25 ? 85.01 ng/mL, p=0.0125) than without infection (2.00 ?15.26 ng/mL). Procalcitonin (cutoff 0.25 or 0.50 ng/mL) did not reliably identify bacterial co-infections, but may be useful in excluding bacterial infection.