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Arch Virol . Antigenic comparison of H3N8 equine influenza viruses belonging to Florida sublineage clade 1 between vaccine strains and North America

tetano

Editor, Senior Moderator
Arch Virol


. 2023 Feb 19;168(3):94.
doi: 10.1007/s00705-023-05720-x.
Antigenic comparison of H3N8 equine influenza viruses belonging to Florida sublineage clade 1 between vaccine strains and North American strains isolated in 2021-2022


Manabu Nemoto[SUP] 1 [/SUP], Stephanie E Reedy[SUP] 2 [/SUP], Takanori Yano[SUP] 3 [/SUP], Kenya Suzuki[SUP] 3 [/SUP], Shino Fukuda[SUP] 3 [/SUP], Marie Garvey[SUP] 4 [/SUP], Yoshinori Kambayashi[SUP] 5 [/SUP], Hiroshi Bannai[SUP] 5 [/SUP], Koji Tsujimura[SUP] 5 [/SUP], Takashi Yamanaka[SUP] 5 [/SUP], Ann Cullinane[SUP] 4 [/SUP], Thomas M Chambers[SUP] 2 [/SUP]



Affiliations

Abstract

Equine influenza virus strains of Florida sublineage clade 1 (Fc1) have been circulating in North America. In this study, virus neutralization assays were performed to evaluate antigenic differences between Fc1 vaccine strains and North American Fc1 strains isolated in 2021-2022, using equine antisera against A/equine/South Africa/4/2003 (a vaccine strain recommended by the World Organisation for Animal Health) and A/equine/Ibaraki/1/2007 (a Japanese vaccine strain). Antibody titers against four North American Fc1 strains isolated in 2021-2022 were comparable to those against the homologous vaccine strains. These results suggest that current Fc1 vaccine strains are effective against North American strains from 2021-2022.

Keywords: Equine influenza virus; Florida sublineage clade 1; Neutralization assay; Vaccine.
 
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