tetano
Editor, Senior Moderator
Arch Virol
. 2023 Jan 3;168(1):19.
doi: 10.1007/s00705-022-05648-8.
Genomic evidence of SARS-CoV-2 reinfection cases in southern Brazil
Ana Paula Muterle Varela[SUP] #[/SUP][SUP] 1 [/SUP], Fernando Hayashi Sant'Anna[SUP] #[/SUP][SUP] 1 [/SUP], Aniúsca Vieira Dos Santos[SUP] 1 [/SUP], Janira Prichula[SUP] 2 [/SUP], Juliana Comerlato[SUP] 1 [/SUP], Giovana Tavares Dos Santos[SUP] 1 [/SUP], Eliana Wendland[SUP] 3 4 [/SUP]
Affiliations
Abstract
Cases of reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported worldwide. We investigated reinfection cases in a set of more than 30,000 samples, and the SARS-CoV-2 genomes from selected samples from four patients with at least two positive diagnoses with an interval ≥ 45 days between tests were sequenced and analyzed. Comparative genomic and phylogenetic analysis confirmed three reinfection cases and suggested that the fourth one was caused by a virus of the same lineage. Viral sequencing is crucial for understanding the natural course of reinfections and for planning public health strategies for management of COVID-19.
. 2023 Jan 3;168(1):19.
doi: 10.1007/s00705-022-05648-8.
Genomic evidence of SARS-CoV-2 reinfection cases in southern Brazil
Ana Paula Muterle Varela[SUP] #[/SUP][SUP] 1 [/SUP], Fernando Hayashi Sant'Anna[SUP] #[/SUP][SUP] 1 [/SUP], Aniúsca Vieira Dos Santos[SUP] 1 [/SUP], Janira Prichula[SUP] 2 [/SUP], Juliana Comerlato[SUP] 1 [/SUP], Giovana Tavares Dos Santos[SUP] 1 [/SUP], Eliana Wendland[SUP] 3 4 [/SUP]
Affiliations
- PMID: 36593369
- DOI: 10.1007/s00705-022-05648-8
Abstract
Cases of reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported worldwide. We investigated reinfection cases in a set of more than 30,000 samples, and the SARS-CoV-2 genomes from selected samples from four patients with at least two positive diagnoses with an interval ≥ 45 days between tests were sequenced and analyzed. Comparative genomic and phylogenetic analysis confirmed three reinfection cases and suggested that the fourth one was caused by a virus of the same lineage. Viral sequencing is crucial for understanding the natural course of reinfections and for planning public health strategies for management of COVID-19.