tetano
Editor, Senior Moderator
BMC Infect Dis
. 2020 Sep 3;20(1):647.
doi: 10.1186/s12879-020-05364-1.
Clinical features and outcomes of seven patients with COVID-19 in a family cluster
Yiling Zhang[SUP] 1 [/SUP], Cheng Zhang[SUP] 1 [/SUP], Ying Hu[SUP] 1 [/SUP], Hongmei Yao[SUP] 1 [/SUP], Xianchun Zeng[SUP] 1 [/SUP], Changrong Hu[SUP] 2 [/SUP], Li Zhao[SUP] 1 [/SUP], Xiangyan Zhang[SUP] 3 [/SUP], Xianwei Ye[SUP] 4 [/SUP]
Affiliations
Abstract
Background: The family cluster is one of most important modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission throughout China, and more details are needed about how family clusters cause the spread of coronavirus disease 2019 (COVID-19).
Case presentation: We retrospectively reviewed 7 confirmed cases from one family cluster. Both clinical features and laboratory examination results were described. Patient 1 had been in close contact with someone who was later confirmed to have COVID-19 in Wuhan City before he returned back to his hometown. He had dinner with 6 other members in his family. All the persons developed COVID-19 successively except for one older woman who neither had dinner with them nor shared a sleeping room with her husband. Six patients had mild or moderate COVID-19 but one older man with underlying diseases progressed into the severe type. After general and symptomatic treatments, all the patients recovered.
Conclusions: In a family cluster, having dinner together may be an important mode for the transmission of SARS-CoV-2. In this setting, most cases are mild with a favorable prognosis, while elderly patients with underlying diseases may progress into the severe type. For someone who has close contact with a confirmed case, 14-day isolation is necessary to contain virus transmission.
Keywords: COVID-19,family cluster; Case report; Clinical features; SARS-CoV-2.
. 2020 Sep 3;20(1):647.
doi: 10.1186/s12879-020-05364-1.
Clinical features and outcomes of seven patients with COVID-19 in a family cluster
Yiling Zhang[SUP] 1 [/SUP], Cheng Zhang[SUP] 1 [/SUP], Ying Hu[SUP] 1 [/SUP], Hongmei Yao[SUP] 1 [/SUP], Xianchun Zeng[SUP] 1 [/SUP], Changrong Hu[SUP] 2 [/SUP], Li Zhao[SUP] 1 [/SUP], Xiangyan Zhang[SUP] 3 [/SUP], Xianwei Ye[SUP] 4 [/SUP]
Affiliations
- PMID: 32883217
- DOI: 10.1186/s12879-020-05364-1
Abstract
Background: The family cluster is one of most important modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission throughout China, and more details are needed about how family clusters cause the spread of coronavirus disease 2019 (COVID-19).
Case presentation: We retrospectively reviewed 7 confirmed cases from one family cluster. Both clinical features and laboratory examination results were described. Patient 1 had been in close contact with someone who was later confirmed to have COVID-19 in Wuhan City before he returned back to his hometown. He had dinner with 6 other members in his family. All the persons developed COVID-19 successively except for one older woman who neither had dinner with them nor shared a sleeping room with her husband. Six patients had mild or moderate COVID-19 but one older man with underlying diseases progressed into the severe type. After general and symptomatic treatments, all the patients recovered.
Conclusions: In a family cluster, having dinner together may be an important mode for the transmission of SARS-CoV-2. In this setting, most cases are mild with a favorable prognosis, while elderly patients with underlying diseases may progress into the severe type. For someone who has close contact with a confirmed case, 14-day isolation is necessary to contain virus transmission.
Keywords: COVID-19,family cluster; Case report; Clinical features; SARS-CoV-2.