tetano
Editor, Senior Moderator
BMC Infect Dis
. 2021 Apr 17;21(1):365.
doi: 10.1186/s12879-021-06037-3.
Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China
Feng Liang[SUP] #[/SUP][SUP] 1 [/SUP], Xianfeng Wang[SUP] #[/SUP][SUP] 2 [/SUP], Jianbo Shao[SUP] #[/SUP][SUP] 3 [/SUP], Jun Chen[SUP] 2 [/SUP], Lei Liu[SUP] 4 [/SUP], Hui Li[SUP] 5 [/SUP], Yi Xu[SUP] 6 [/SUP], Liya He[SUP] 6 7 [/SUP], Huiying Liang[SUP] 1 7 [/SUP], Kuanrong Li[SUP] 8 [/SUP], Sitang Gong[SUP] 6 7 [/SUP], Huimin Xia[SUP] 1 7 [/SUP]
Affiliations
Abstract
Background: Coronavirus disease 2019 (COVID-19) share similar symptoms with influenza A (IA), but it is more worthwhile to understand the disparities of the two infections regarding their clinical characteristics on admission.
Methods: A total of 71 age-matched pediatric IA and COVID-19 patient pairs were formed and their clinical data on admission were compared.
Results: Fever, cough, nasal congestion and nausea/vomiting were the most common symptoms on admission for both infections but occurred less often in COVID-19. The IA patients were more likely to have lower-than-normal levels of lymphocyte count and percentage and to have higher-than-normal levels of activated partial thromboplastin time, prothrombin time, serum C-reactive protein, and serum procalcitonin, while the COVID-19 patients had higher odds of having lower-than-normal levels of neutrophil count and percentage.
Conclusions: This study suggests that influenza A is more symptomatic than COVID-19 for children and might be an overall more severe infection at the time of admission.
Keywords: Coronavirus disease 2019; Influenza a; Pediatrics; Retrospective study.
. 2021 Apr 17;21(1):365.
doi: 10.1186/s12879-021-06037-3.
Comparison of clinical features on admission between coronavirus disease 2019 and influenza a among children: a retrospective study in China
Feng Liang[SUP] #[/SUP][SUP] 1 [/SUP], Xianfeng Wang[SUP] #[/SUP][SUP] 2 [/SUP], Jianbo Shao[SUP] #[/SUP][SUP] 3 [/SUP], Jun Chen[SUP] 2 [/SUP], Lei Liu[SUP] 4 [/SUP], Hui Li[SUP] 5 [/SUP], Yi Xu[SUP] 6 [/SUP], Liya He[SUP] 6 7 [/SUP], Huiying Liang[SUP] 1 7 [/SUP], Kuanrong Li[SUP] 8 [/SUP], Sitang Gong[SUP] 6 7 [/SUP], Huimin Xia[SUP] 1 7 [/SUP]
Affiliations
- PMID: 33865314
- DOI: 10.1186/s12879-021-06037-3
Abstract
Background: Coronavirus disease 2019 (COVID-19) share similar symptoms with influenza A (IA), but it is more worthwhile to understand the disparities of the two infections regarding their clinical characteristics on admission.
Methods: A total of 71 age-matched pediatric IA and COVID-19 patient pairs were formed and their clinical data on admission were compared.
Results: Fever, cough, nasal congestion and nausea/vomiting were the most common symptoms on admission for both infections but occurred less often in COVID-19. The IA patients were more likely to have lower-than-normal levels of lymphocyte count and percentage and to have higher-than-normal levels of activated partial thromboplastin time, prothrombin time, serum C-reactive protein, and serum procalcitonin, while the COVID-19 patients had higher odds of having lower-than-normal levels of neutrophil count and percentage.
Conclusions: This study suggests that influenza A is more symptomatic than COVID-19 for children and might be an overall more severe infection at the time of admission.
Keywords: Coronavirus disease 2019; Influenza a; Pediatrics; Retrospective study.