tetano
Editor, Senior Moderator
BMC Infect Dis
. 2021 Jul 26;21(1):706.
doi: 10.1186/s12879-021-06394-z.
Lower urinary tract signs and symptoms in patients with COVID-19
Aida Javan Balegh Marand[SUP] 1 2 3 [/SUP], Christian Bach[SUP] 1 [/SUP], Dick Janssen[SUP] 2 [/SUP], John Heesakkers[SUP] 2 [/SUP], Morteza Ghojazadeh[SUP] 4 [/SUP], Thomas Alexander Vögeli[SUP] 1 [/SUP], Hanieh Salehi-Pourmehr[SUP] 4 [/SUP], Hadi Mostafae[SUP] 5 [/SUP], Sakineh Hajebrahimi[SUP] 4 [/SUP], Mohammad Sajjad Rahnama'i[SUP] 6 7 [/SUP]
Affiliations
Abstract
Background: The type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic. It is not clear if COVID-19 patients have any lower urinary tract signs or symptoms.
Methods: The effect of COVID-19 on lower urinary tract function was studied in a prospective multi-centre, observational study including 238 patients who were admitted with symptoms caused by COVID-19 to the university hospital of Aachen in Germany and Tabriz in Iran.
Results: None of the patients reported to have any lower urinary tract symptoms. SARS-CoV-2 was found in the urine of 19% of the tested patients. The mortality rate in COVID-19 infected patients with microscopic haematuria together with white blood cells in their urine, was significantly increased from 48 to 61% in the Tabriz cohort (p-value = 0.03) and from 30 to 35% in the Aachen cohort (p-value =0.045). Furthermore, in the group of patients with SARS-CoV-2 urine PCR, the mortality rate rose from 30 to 58%. (p-value =0.039).
Conclusion: Patients admitted with COVID-19 did not report to have any lower urinary tract symptoms, even those patient who had a positive Urine SARS-CoV-2 PCR. In addition, hematuria, WBC in urine as well as SARS- CoV-2 presence in urine, were found to be strong negative prognostic factors in admitted COVID-19 patients.
Keywords: COVID-19; Hematuria; Lower urinary tract symptoms (LUTS); SARS-CoV-2; Urine, leukocyturia.
. 2021 Jul 26;21(1):706.
doi: 10.1186/s12879-021-06394-z.
Lower urinary tract signs and symptoms in patients with COVID-19
Aida Javan Balegh Marand[SUP] 1 2 3 [/SUP], Christian Bach[SUP] 1 [/SUP], Dick Janssen[SUP] 2 [/SUP], John Heesakkers[SUP] 2 [/SUP], Morteza Ghojazadeh[SUP] 4 [/SUP], Thomas Alexander Vögeli[SUP] 1 [/SUP], Hanieh Salehi-Pourmehr[SUP] 4 [/SUP], Hadi Mostafae[SUP] 5 [/SUP], Sakineh Hajebrahimi[SUP] 4 [/SUP], Mohammad Sajjad Rahnama'i[SUP] 6 7 [/SUP]
Affiliations
- PMID: 34311703
- DOI: 10.1186/s12879-021-06394-z
Abstract
Background: The type of pneumonia that is caused by the new coronavirus (SARS-CoV-2) has spread across the world in a pandemic. It is not clear if COVID-19 patients have any lower urinary tract signs or symptoms.
Methods: The effect of COVID-19 on lower urinary tract function was studied in a prospective multi-centre, observational study including 238 patients who were admitted with symptoms caused by COVID-19 to the university hospital of Aachen in Germany and Tabriz in Iran.
Results: None of the patients reported to have any lower urinary tract symptoms. SARS-CoV-2 was found in the urine of 19% of the tested patients. The mortality rate in COVID-19 infected patients with microscopic haematuria together with white blood cells in their urine, was significantly increased from 48 to 61% in the Tabriz cohort (p-value = 0.03) and from 30 to 35% in the Aachen cohort (p-value =0.045). Furthermore, in the group of patients with SARS-CoV-2 urine PCR, the mortality rate rose from 30 to 58%. (p-value =0.039).
Conclusion: Patients admitted with COVID-19 did not report to have any lower urinary tract symptoms, even those patient who had a positive Urine SARS-CoV-2 PCR. In addition, hematuria, WBC in urine as well as SARS- CoV-2 presence in urine, were found to be strong negative prognostic factors in admitted COVID-19 patients.
Keywords: COVID-19; Hematuria; Lower urinary tract symptoms (LUTS); SARS-CoV-2; Urine, leukocyturia.