tetano
Editor, Senior Moderator
BMC Infect Dis
. 2024 Dec 19;24(1):1449.
doi: 10.1186/s12879-024-10308-0. Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID
Asia Avinir[SUP] 1 [/SUP], Aviv Kupershmidt[SUP] 2 [/SUP], Dana Amsterdam[SUP] 2 [/SUP], Guy Choshen[SUP] 3 [/SUP], Jacob Nadav Ablin[SUP] #[/SUP][SUP] 2 4 [/SUP], Odelia Elkana[SUP] #[/SUP][SUP] 5 6 [/SUP]
Affiliations
Objective: This study investigates persistent physical and neuropsychiatric symptoms in Long COVID, focusing on their severity and assessing risk/resilience factors, including conscientiousness and neuroticism. The study utilizes a mediation model to explore the potential role of psychological distress in mediating its impact on cognitive decline.
Methods: In an online survey, 114 participants diagnosed with Long COVID completed assessments, including the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) for psychological distress, Subjective Cognitive Decline (SCD) questionnaire for cognitive decline, Pittsburgh Sleep Quality Index (PSQI) for sleep disorders, and Multidimensional Scale of Perceived Social Support (MSPSS) with "BIG-5 inventory" subscales for risk/resilience factors.
Results: Findings showed high rates of depressive disorders (45.6%), generalized anxiety disorders (21%), sleep disturbances (76.3%), and reported cognitive changes (94.7%). Conscientiousness negatively correlated with psychological distress (p < .001, r = - .48) and cognitive decline (p < .001, r = - .36), while neuroticism positively correlated (p < .001, r = .62 and p < .001, r = .41, respectively). Social support negatively correlated with psychological distress (p < .001, r = - .52) and cognitive decline (p < .001, r = - .41). Psychological distress fully mediated personality traits and cognitive decline correlations, with significant full mediation for neuroticism [95% CI = (0.22, 0.48)] and conscientiousness [95% CI = (-0.33, -0.07)], controlling for age, gender, other chronic morbidity and social support.
Conclusion: The study underscores the significance of incorporating psychological interventions into treatment plans to alleviate distress symptoms associated with cognitive decline in conditions like Long COVID.
Keywords: Conscientiousness; Long covid; Neuroticism; Personality traits; Psychological distress, subjective cognitive decline (SCD).
. 2024 Dec 19;24(1):1449.
doi: 10.1186/s12879-024-10308-0. Personality and neuropsychiatric symptoms in individuals diagnosed with long COVID
Asia Avinir[SUP] 1 [/SUP], Aviv Kupershmidt[SUP] 2 [/SUP], Dana Amsterdam[SUP] 2 [/SUP], Guy Choshen[SUP] 3 [/SUP], Jacob Nadav Ablin[SUP] #[/SUP][SUP] 2 4 [/SUP], Odelia Elkana[SUP] #[/SUP][SUP] 5 6 [/SUP]
Affiliations
- PMID: 39702051
- PMCID: PMC11658332
- DOI: 10.1186/s12879-024-10308-0
Objective: This study investigates persistent physical and neuropsychiatric symptoms in Long COVID, focusing on their severity and assessing risk/resilience factors, including conscientiousness and neuroticism. The study utilizes a mediation model to explore the potential role of psychological distress in mediating its impact on cognitive decline.
Methods: In an online survey, 114 participants diagnosed with Long COVID completed assessments, including the Patient Health Questionnaire (PHQ-9) and Generalized Anxiety Disorder (GAD-7) for psychological distress, Subjective Cognitive Decline (SCD) questionnaire for cognitive decline, Pittsburgh Sleep Quality Index (PSQI) for sleep disorders, and Multidimensional Scale of Perceived Social Support (MSPSS) with "BIG-5 inventory" subscales for risk/resilience factors.
Results: Findings showed high rates of depressive disorders (45.6%), generalized anxiety disorders (21%), sleep disturbances (76.3%), and reported cognitive changes (94.7%). Conscientiousness negatively correlated with psychological distress (p < .001, r = - .48) and cognitive decline (p < .001, r = - .36), while neuroticism positively correlated (p < .001, r = .62 and p < .001, r = .41, respectively). Social support negatively correlated with psychological distress (p < .001, r = - .52) and cognitive decline (p < .001, r = - .41). Psychological distress fully mediated personality traits and cognitive decline correlations, with significant full mediation for neuroticism [95% CI = (0.22, 0.48)] and conscientiousness [95% CI = (-0.33, -0.07)], controlling for age, gender, other chronic morbidity and social support.
Conclusion: The study underscores the significance of incorporating psychological interventions into treatment plans to alleviate distress symptoms associated with cognitive decline in conditions like Long COVID.
Keywords: Conscientiousness; Long covid; Neuroticism; Personality traits; Psychological distress, subjective cognitive decline (SCD).