tetano
Editor, Senior Moderator
BMC Pregnancy Childbirth
. 2020 Oct 6;20(1):587.
doi: 10.1186/s12884-020-03275-2.
SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report
Alejandro Garcia Rodriguez[SUP] 1 [/SUP], Sergio Marcos Contreras[SUP] 2 [/SUP], Santiago Manuel Fernandez Manovel[SUP] 1 [/SUP], Jose Miguel Marcos Vidal[SUP] 1 [/SUP], Fernando Diez Buron[SUP] 1 [/SUP], Camino Fernandez Fernandez[SUP] 3 [/SUP], Maria Del Carmen Riveira Gonzalez[SUP] 4 [/SUP]
Affiliations
Abstract
Background: There are no published cases of tonic-clonic seizures and posterior bilateral blindness during pregnancy and Severe Acute Respiratory Syndrome (SARS) Coronavirus (COV) 2 (SARS-COV-2) infection. We do not just face new and unknown manifestations, but also how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. Coronavirus Disease 2019 (COVID-19), preeclampsia, eclampsia and posterior reversible leukoencephalopathy share endothelium damage and similar pathophysiology.
Case presentation: A 35-year-old pregnant woman was admitted for tonic-clonic seizures and SARS-COV-2 infection. She had a normal pregnancy control and no other symptoms before tonic-clonic seizures development. After a Caesarean section (C-section) she developed high blood pressure, and we initiated antihypertensive treatment with labetalol, amlodipine and captopril. Few hours later she developed symptoms of cortical blindness that resolved in 72 h with normal brain computed tomography (CT) angiography.
Conclusion: The authors conclude that SARS COV-2 infection could promote brain endothelial damage and facilitate neurological complications during pregnancy.
Keywords: COVID-19; Case-report; Neurological manifestations; Preeclampsia; Pregnancy.
. 2020 Oct 6;20(1):587.
doi: 10.1186/s12884-020-03275-2.
SARS-COV-2 infection during pregnancy, a risk factor for eclampsia or neurological manifestations of COVID-19? Case report
Alejandro Garcia Rodriguez[SUP] 1 [/SUP], Sergio Marcos Contreras[SUP] 2 [/SUP], Santiago Manuel Fernandez Manovel[SUP] 1 [/SUP], Jose Miguel Marcos Vidal[SUP] 1 [/SUP], Fernando Diez Buron[SUP] 1 [/SUP], Camino Fernandez Fernandez[SUP] 3 [/SUP], Maria Del Carmen Riveira Gonzalez[SUP] 4 [/SUP]
Affiliations
- PMID: 33023500
- DOI: 10.1186/s12884-020-03275-2
Abstract
Background: There are no published cases of tonic-clonic seizures and posterior bilateral blindness during pregnancy and Severe Acute Respiratory Syndrome (SARS) Coronavirus (COV) 2 (SARS-COV-2) infection. We do not just face new and unknown manifestations, but also how different patient groups are affected by SARS-COV-2 infection, such as pregnant women. Coronavirus Disease 2019 (COVID-19), preeclampsia, eclampsia and posterior reversible leukoencephalopathy share endothelium damage and similar pathophysiology.
Case presentation: A 35-year-old pregnant woman was admitted for tonic-clonic seizures and SARS-COV-2 infection. She had a normal pregnancy control and no other symptoms before tonic-clonic seizures development. After a Caesarean section (C-section) she developed high blood pressure, and we initiated antihypertensive treatment with labetalol, amlodipine and captopril. Few hours later she developed symptoms of cortical blindness that resolved in 72 h with normal brain computed tomography (CT) angiography.
Conclusion: The authors conclude that SARS COV-2 infection could promote brain endothelial damage and facilitate neurological complications during pregnancy.
Keywords: COVID-19; Case-report; Neurological manifestations; Preeclampsia; Pregnancy.