tetano
Editor, Senior Moderator
BMC Res Notes
. 2024 Jan 4;17(1):14.
doi: 10.1186/s13104-023-06677-5. Outcomes of patients with COVID-19 and coronary artery disease and heart failure: findings from the Philippine CORONA study
Adrian I Espiritu[SUP] #[/SUP][SUP] 1 2 [/SUP], John Christopher A Pilapil[SUP] #[/SUP][SUP] 3 [/SUP], Jaime Alfonso M Aherrera[SUP] #[/SUP][SUP] 3 [/SUP], Marie Charmaine C Sy[SUP] 1 [/SUP], Veeda Michelle M Anlacan[SUP] 1 [/SUP], Emilio Q Iii Villanueva[SUP] 4 [/SUP], Roland Dominic G Jamora[SUP] 5 6 [/SUP]
Affiliations
Background: Patients with coronavirus disease 2019 (COVID-19) and coronary artery disease (CAD) or heart failure (HF) are more likely to have poor outcomes. This study aimed to determine the characteristics and outcomes of COVID-19 patients with CAD/HF across various institutions in the Philippines.
Methods: We utilized the data from the Philippine CORONA Study and compared the outcomes of admitted COVID-19 patients with CAD/HF versus those without. The Student's t test, Mann-Whitney U test, binary logistic regression and multivariate regression analysis were utilized. Odds ratios (OR) and Kaplan-Meier curves were generated.
Results: We included a total of 512 patients with COVID-19 had CAD/HF and 10,369 were without. CAD/HF was significantly associated with COVID severity, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization. After adjusting for confounders, the presence of CAD/HF was still associated with death from a cardiac cause (OR 2.22, 95% CI 1.49-3.3, p < 0.01).
Conclusions: The presence of CAD or HF was significantly associated with severity of COVID disease, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization.
Keywords: COVID-19; Coronary artery disease; Heart failure; Hospital stay; Intensive care unit admission; Mortality; Respiratory failure.
. 2024 Jan 4;17(1):14.
doi: 10.1186/s13104-023-06677-5. Outcomes of patients with COVID-19 and coronary artery disease and heart failure: findings from the Philippine CORONA study
Adrian I Espiritu[SUP] #[/SUP][SUP] 1 2 [/SUP], John Christopher A Pilapil[SUP] #[/SUP][SUP] 3 [/SUP], Jaime Alfonso M Aherrera[SUP] #[/SUP][SUP] 3 [/SUP], Marie Charmaine C Sy[SUP] 1 [/SUP], Veeda Michelle M Anlacan[SUP] 1 [/SUP], Emilio Q Iii Villanueva[SUP] 4 [/SUP], Roland Dominic G Jamora[SUP] 5 6 [/SUP]
Affiliations
- PMID: 38178236
- DOI: 10.1186/s13104-023-06677-5
Background: Patients with coronavirus disease 2019 (COVID-19) and coronary artery disease (CAD) or heart failure (HF) are more likely to have poor outcomes. This study aimed to determine the characteristics and outcomes of COVID-19 patients with CAD/HF across various institutions in the Philippines.
Methods: We utilized the data from the Philippine CORONA Study and compared the outcomes of admitted COVID-19 patients with CAD/HF versus those without. The Student's t test, Mann-Whitney U test, binary logistic regression and multivariate regression analysis were utilized. Odds ratios (OR) and Kaplan-Meier curves were generated.
Results: We included a total of 512 patients with COVID-19 had CAD/HF and 10,369 were without. CAD/HF was significantly associated with COVID severity, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization. After adjusting for confounders, the presence of CAD/HF was still associated with death from a cardiac cause (OR 2.22, 95% CI 1.49-3.3, p < 0.01).
Conclusions: The presence of CAD or HF was significantly associated with severity of COVID disease, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization.
Keywords: COVID-19; Coronary artery disease; Heart failure; Hospital stay; Intensive care unit admission; Mortality; Respiratory failure.