tetano
Editor, Senior Moderator
Braz J Infect Dis. 2020 May 6. pii: S1413-8670(20)30043-X. doi: 10.1016/j.bjid.2020.04.009. [Epub ahead of print]
An infant with a mild SARS-CoV-2 infection detected only by anal swabs: a case report.
Li J[SUP]1[/SUP], Feng J[SUP]1[/SUP], Liu TH[SUP]2[/SUP], Xu FC[SUP]2[/SUP], Song GQ[SUP]3[/SUP].
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Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and has spread rapidly worldwide. We present a mild SARS-CoV-2 infection in a baby with non-productive cough and normal chest computed tomography, in whom only anal swabs tested positive by real-time PCR testing for SARS-CoV-2. She was given atomization inhalation therapy with recombinant human interferon alfa-1b for 10 days. Her anal swabs remained positive for eight days, whereas her throat swabs were persistently negative by real-time PCR testing. Mild and asymptomatic cases, especially in children, might present with PCR negative pharyngeal/nasal swabs and PCR positive anal swabs. Those patients are potential sources of infection via fecal-oral transmission for COVID-19.
Copyright ? 2020. Published by Elsevier Espa?a, S.L.U.
KEYWORDS:
Anal swab; Baby; Severe acute respiratory syndrome coronavirus 2
PMID:32389618DOI:10.1016/j.bjid.2020.04.009
Free full text
An infant with a mild SARS-CoV-2 infection detected only by anal swabs: a case report.
Li J[SUP]1[/SUP], Feng J[SUP]1[/SUP], Liu TH[SUP]2[/SUP], Xu FC[SUP]2[/SUP], Song GQ[SUP]3[/SUP].
Author information
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) emerged in Wuhan, China and has spread rapidly worldwide. We present a mild SARS-CoV-2 infection in a baby with non-productive cough and normal chest computed tomography, in whom only anal swabs tested positive by real-time PCR testing for SARS-CoV-2. She was given atomization inhalation therapy with recombinant human interferon alfa-1b for 10 days. Her anal swabs remained positive for eight days, whereas her throat swabs were persistently negative by real-time PCR testing. Mild and asymptomatic cases, especially in children, might present with PCR negative pharyngeal/nasal swabs and PCR positive anal swabs. Those patients are potential sources of infection via fecal-oral transmission for COVID-19.
Copyright ? 2020. Published by Elsevier Espa?a, S.L.U.
KEYWORDS:
Anal swab; Baby; Severe acute respiratory syndrome coronavirus 2
PMID:32389618DOI:10.1016/j.bjid.2020.04.009
Free full text