Brazil: Tamiflu is not as effective as you think, says secretary

[Gert van der Hoek]

google translated

Thursday, September 17, 2009, 10:29

Tamiflu is not as effective as you think, says secretary

The Secretariat of Health of Ontario announced on Wednesday a survey that questioned the effectiveness of Oseltamivir (Tamiflu) in the fight against swine flu. According to the secretariat, there is little difference between using or not the drug.

According to a survey conducted by Central State Hospital Setting through August, the patients admitted to intensive care units (ICUs) in the State that had given the medication within 48 hours after the first symptoms (as indicated by the manufacturer), 18 were discharged and 12 died, of those who took Tamiflu after that period, 18 left the hospital and 14 did not survive, people who had administered the drug, 15 were discharged and six died.

According to the secretariat, the data indicate that there is a difference between natural or not to use Tamiflu to combat the disease. However, the court said it would continue administering the drug to patients.

Until Sept. 12, when the last survey, 59 patients were in ICU in the state with swine flu or suspected disease. However, the peak of the epidemic - in August - more than 270 people were hospitalized in intensive care units.

http://noticias.terra.com.br/gripes...ao+eficaz+quanto+se+pensa+diz+secretaria.html

 

[tropical]

Re: Brazil: Tamiflu is not as effective as you think, says secretary

#1: ... 48 h ...


Apart an resistance strain appearance which can be than checked from the hospitalized, and without specific med efectiveness diatribes,


it could be at work the problematic catch of "+48 hours from which moment"?

Who can say precisely at which time started the very early pandemic flu symptoms?

They all worldwide mainly stick to the now proved wrong perception of insurged temperature, and visible symptoms, or known direct exposure with an flu illnesed. This kind of measurement of the moment zero could be largely wrong, because the eye visible or temp. measurable onset of symptoms could be only many days after the appearance of the first very tenue or unsignificant symptoms - so the real timeline of the "in 48 hours administered Tamiflu" could be:
48h + several days,
which than represent a failure for sucessful treatments.

Even if we take an example of light, mostly unnoticed symptom as light cough:
how many people will call a doctor or go there and got Tamiflu pils to drop in, if they have only a light cough few times daily, without any temperature, and without any other symptom during several days?

Almost none.

But further, such few/several days of light cough - which in fact represents the first symptoms onset, could few days later develop in much more heavy and frequent cough, which could than after few days maybe lead to a temperature onset, but maybe not also.

In the above light cough example, the administration of in time (48h, but it is realy stated 24h for the most optimal results) were largely missed, because probable it will be taken only after several days - after the heavy cough appearance, or even a week after - if the surge in temperature is a triger for treatments.

 

[Giuseppe]

Re: Brazil: Tamiflu is not as effective as you think, says secretary

From Sept. 21, 2009 ECDC update

On ECDC site: http://www.ecdc.europa.eu/en/health..._Influenza_AH1N1_Situation_Report_0900hrs.pdf

On FT:
http://www.flutrackers.com/forum/showpost.php?p=296721&postcount=52
(...)

Brazil Ministry of Health expressed doubts about oseltamivir treatment

According to Brazilian media reports, a study describing the treatment of 83 critically ill patients in Rio Grande du Sol could not show any increase in survival rates of patients treated with oseltamivir within 48 hours of infection. The results of this unpublished study were presented to the media by the Secretary of Health of Rio Grande du Sol.

(...)

 

[Gert van der Hoek]

Re: Brazil: Tamiflu is not as effective as you think, says secretary

Too bad the study is not published, we are left in the dark, still many questions to be answered.

 

[Snowy Owl]

Re: Brazil: Tamiflu is not as effective as you think, says secretary

Japan who used to be the highest consumers of Tamiflu as produce a lot of datas but few made the MSN.

You can find then at the Japan Paharmaco-Vigilance Institute

here is what are there datas

<table width="800" align="center" border="0"><tbody><tr><td align="center"> Paper on "Fatal Adverse Reactions to Tamiflu" is now published
---case series and overview of causal relationships </td> </tr> <tr> <td>
</td> <td align="right"> By Rokuro Hama　M.D. (Chairperson, Kusuri-no-Check)Jun. 23, 2008 </td></tr></tbody></table><table width="800" align="center" border="0"><tbody><tr><td align="center">Tamiflu-induced encephalopathy is ?yakugai (drug disaster)? </td> </tr> <tr> <td>
</td> <td align="right"> by HAMA, R. MD (Kusuri-no-Check) Feb. 1, 2007 </td></tr></tbody></table>Snowy

Remember if you go against Roche you go against Gilead whose major owners is a certain Ronald Rumsfeld, yes the former Defense Secretary

Be careful to present corroborated analysis

Snowy OWl

 

[Labrador - Sadie]

Re: Brazil: Tamiflu is not as effective as you think, says secretary

Remember if you go against Roche you go against Gilead whose major owners is a certain Ronald Rumsfeld, yes the former Defense Secretary

Be careful to present corroborated analysis

Snowy OWl

I believe you are referring to Donald Rumsfeld.

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