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Canada - Man confirmed H1N1v positive after contact with pigs in Ontario

sharon sanders

Editor-in-Chief & President
Case of Influenza A H1N1 Variant Detected in Ontario




September 25, 2012 8:00 AM
Today, Dr. Arlene King, Ontario's Chief Medical Officer of Health, issued the following statement on a case of influenza A H1N1 variant detected in Ontario:


"An Ontario resident has been confirmed as having been infected with an H1N1 variant (H1N1v) influenza virus. An influenza virus that normally circulates in animals is referred to as a variant virus when it infects humans.


This adult male patient became ill after close contact with pigs. He is being treated and closely monitored in a hospital in southwestern Ontario.
I would like to reassure Ontarians that this variant influenza virus rarely spreads from animals to humans. Subsequent human-to-human transmission is also rare. I would also like to stress that this is not a food safety issue; the consumption of properly cooked pork continues to be safe. Proper cooking of meats, including pork, kills all bacteria and viruses.
Ontarians should remember that hand washing is the single best infection prevention and control measure against respiratory illnesses such as influenza. Individuals should wash their hands often with soap and running water, or use an alcohol-based hand rub if soap and water are not available.


I also would like to remind Ontarians that it is important to get immunized every year with the seasonal flu vaccine when it becomes available each fall. This will protect you against seasonal influenza viruses that are expected to circulate. Everyone six months of age and older should get the seasonal flu vaccine each year.


The identification of this case is the result of the strength of our current surveillance system here in Ontario. It is not an unexpected occurrence and there have been a number of human infections with variant influenza viruses in the United States over the past year.


I would like to thank health officials in Ontario who displayed the utmost vigilance in identifying, treating and closely investigating this case. Protecting the health of Ontarians is a priority and we will continue to monitor the situation."


http://news.ontario.ca/mohltc/en/2012/09/case-of-influenza-a-h1n1-variant-detected-in-ontario.html
 
Re: Canada - Man confirmed H1N1v positive after contact with pigs in Ontario

H1N1-variant swine flu spotted in Ontario

Not linked to flu at U.S. fairs this summer

By Helen Branswell, THE CANADIAN PRESS
September 25, 2012 10:21 AM

TORONTO ? Ontario has found a case of an infection with a new swine flu virus, in a man who had close contact with pigs.

The infection was caused by an H1N1-variant virus, which is not the swine flu virus that has been jumping from pigs to people in the United States this summer.

That virus, an H3N2-variant, has caused 305 infections this year in the U.S. but has not been spotted in Canada to date. Most infections with the H3N2-variant flu have been in people who visited pig barns at state and county fairs.
...
U.S. authorities have also seen one case of infection with an H1N1v virus there this summer, in Missouri. King did not say whether the genetic blueprints of the Ontario and Missouri viruses were closely related.

Read more: http://www.montrealgazette.com/H1N1+variant+swine+spotted+Ontario/7295776/story.html#ixzz27UdjynUI
 
Re: Canada - Man confirmed H1N1v positive after contact with pigs in Ontario

Source: http://www.thestar.com/news/canada/article/1261803--h1n1-case-confirmed-in-ontario


Ontario reports first pig-to-human H1N1 case
Published 35 minutes ago
Richard J. Brennan
National Affairs Writer


The first case in Ontario of a human contracting the H1N1 variant influenza virus from a pig has been confirmed, the province?s Chief Medical Officer said Tuesday.

?It is a first for us in Ontario,? Dr. Arlene King told the Star Tuesday.

King said an adult male, who is in critical but stable condition in hospital, came down with symptoms of the influenza virus strain after close contact with pigs either in Canada or the U.S. The case was confirmed Sept. 23 after laboratory tests were conducted.

King flatly refused to say where the case was confirmed...
 
Re: Canada - Man confirmed H1N1v positive after contact with pigs in Ontario

Apparently, this is a severe case:

http://www.bizjournals.com/buffalo/...2/09/first-pig-to-human-transmission-of.html?

First pig-to-human transmission of H1N1 is confirmed
Date: Wednesday, September 26, 2012, 7:14am EDT

Ontario has identified its first case of a human contracting the H1N1 virus from a pig.

The province's chief medical officer confirmed the case to the Toronto Star, but declined to say where the person lives.

The adult male is reportedly in critical but stable condition in an Ontario hospital. H1N1 is a variant influenza virus.

?I think it?s important to remember that this does not pose a threat to the public (generally),? said Arlene King, Ontario's chief medical officer.

[snip]
 
Re: Canada - Man confirmed H1N1v positive after contact with pigs in Ontario

INFLUENZA (93): CANADA (ONTARIO), H1N1V, SEQUENCE DATA

Published Date: 2012-09-28 11:22:27
Subject: PRO/AH/EDR> Influenza (93): Canada (ON) H1N1v, sequence data
Archive Number: 20120928.1312982

INFLUENZA (93): CANADA (ONTARIO), H1N1V, SEQUENCE DATA
******************************************************
A ProMED-mail post
http://www.promedmail.org
ProMED-mail is a program of the
International Society for Infectious Diseases
http://www.isid.org


Date: Thu 27 Sep 2012

From: Anne Winter [edited]





[Previously it was reported in ProMED-mail post: Influenza (91): Canada (ON) H1N1v, human case 20120926.1311060 that it had not been confirmed that the M gene of the pandemic H1N1 virus, which is also present in the swine flu viruses that have been causing human infections in the USA this summer 2012, was present in the Canadian isolate. In fact, the complete sequence had been obtained, and the relevant data are presented below. - Mod.CP]



* PCR and sequencing results of HA and NA showed that this virus is an H1N1 subtype, which is closely related to H1N1 swine triple reassortant viruses identified in the United States in 2011 and 2012



* Sequencing revealed that this H1N1 carries the M gene of influenza A(H1N1)pdm09, as was found in the last 2 documented cases of H1N1v infection, in Wisconsin (December 2011) and Missouri (reported September 2012).



Based on the testing results from PHOL and NML, we conclude that this patient was infected with an influenza A H1N1 variant (H1N1v) virus.



* The HA gene was found to have nucleotide sequence homologies of:

* 98.8 percent to the HA of the H1N1v reported in Missouri earlier this month [September 2012].

* 96.2 percent to the HA of the H1N1v reported in Wisconsin in December 2011

* 92 percent to the HA of A/California/7/2009 (H1N1)-like virus, the A(H1N1)pdm09 strain in the current seasonal influenza vaccine.



Based on data from the US Centers for Disease Control and Prevention, 2 H1N1v viruses (A/Wisconsin and A/Missouri) isolated from humans in the US in 2011 and 2012, separately, are closely related antigenically to A/California/7/2009 virus, which is a vaccine component of the currently available influenza vaccine. It is expected that the 2012-2013 seasonal influenza vaccine is likely to protect against the H1N1v influenza virus, although the seasonal influenza vaccine may not protect people against some other variant influenza viruses that are very different from currently circulating human influenza viruses.



J.B.Gubbay1,2, Y.Li3, D.J. Farrell1,2, A.L. Winter1, E. Kristjanson1, A. Li1, A. Eshaghi1, P. Rosenfeld1, R.Wheeler1 F. Plummer3, F. Jamieson1,2.



1. Public Health Ontario, Canada.

2. University of Toronto, Toronto, Ontario, Canada.

3. National Microbiology Laboratory, Public Health Agency of Canada.



--

Anne Winter RN, BScN, MHSc, CIC: Manager (A) Surveillance Services

Communicable Disease Prevention and Control

Public Health Ontario

480 University Avenue, Suite 300

Toronto, ON, Canada M5G 1V2

[ProMED-mail thanks the authors for this clarification. - Mod.CP

A HealthMap/ProMED-mail map can be accessed at: http://healthmap.org/r/1tBo.]
 
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