tetano
Editor, Senior Moderator
Cardiology
. 2023 Aug 16.
doi: 10.1159/000533359. Online ahead of print.
Pathological interplay and clinical complications between COVID-19 and cardiovascular diseases: an overview in 2023
Sufeng Zhou, Anchen Zhang, Hua Liao, Zhebo Liu, Feiyan Yang
The coronavirus disease 2019 (COVID-19) involves all organs of the body, of which the interaction with cardiovascular diseases is the most important. Numerous studies have reported that COVID-19 patients complicated with cardiovascular comorbidities (hypertension, coronary heart disease, chronic heart failure, cerebrovascular disease) are more likely to develop into critical illness and have higher mortality. Conversely, COVID-19 may also cause myocardial injury in patients through various pathological mechanisms such as direct virus attack on cardiomyocytes, overactivation of immune response, microthrombus formation, which may lead to fatal acute ST-segment elevation myocardial infarction, arrhythmia, acute worsening of chronic heart failure, etc. In addition, the symptoms of the so-called long-COVID may remain in some patients who survived the acute viral infection. Positional tachycardia has been widely reported, and cardiovascular autonomic disorders are thought to play a pathogenic role.
. 2023 Aug 16.
doi: 10.1159/000533359. Online ahead of print.
Pathological interplay and clinical complications between COVID-19 and cardiovascular diseases: an overview in 2023
Sufeng Zhou, Anchen Zhang, Hua Liao, Zhebo Liu, Feiyan Yang
- PMID: 37586358
- DOI: 10.1159/000533359
The coronavirus disease 2019 (COVID-19) involves all organs of the body, of which the interaction with cardiovascular diseases is the most important. Numerous studies have reported that COVID-19 patients complicated with cardiovascular comorbidities (hypertension, coronary heart disease, chronic heart failure, cerebrovascular disease) are more likely to develop into critical illness and have higher mortality. Conversely, COVID-19 may also cause myocardial injury in patients through various pathological mechanisms such as direct virus attack on cardiomyocytes, overactivation of immune response, microthrombus formation, which may lead to fatal acute ST-segment elevation myocardial infarction, arrhythmia, acute worsening of chronic heart failure, etc. In addition, the symptoms of the so-called long-COVID may remain in some patients who survived the acute viral infection. Positional tachycardia has been widely reported, and cardiovascular autonomic disorders are thought to play a pathogenic role.