tetano
Editor, Senior Moderator
Case Rep Ophthalmol Med
. 2021 Jul 16;2021:7336488.
doi: 10.1155/2021/7336488. eCollection 2021.
Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
Monica P Gonzalez[SUP] 1 [/SUP], Radames Rios[SUP] 1 [/SUP], Mariella Pappaterra[SUP] 1 [/SUP], Miguel Hernandez[SUP] 2 [/SUP], Allison Toledo[SUP] 3 [/SUP], Carmen Santos[SUP] 1 [/SUP], Andres Emanuelli[SUP] 1 3 [/SUP], Shree K Kurup[SUP] 1 4 [/SUP], Armando L Oliver[SUP] 1 [/SUP]
Affiliations
Abstract
Purpose: To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection.
Methods: Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision loss, pain, redness, and photophobia. An ophthalmological examination revealed findings consistent with acute retinal necrosis of the right eye. A polymerase chain reaction (PCR) analysis of the right vitreous was positive for herpes simplex virus type 2 (HSV-2). A coronavirus disease 2019 (COVID-19) screening test using reverse transcriptase- (RT-) PCR was positive for SARS-CoV-2 RNA.
Conclusions: Our case suggests that COVID-19 may cause a latent HSV infection to reactivate, causing contralateral involvement in patients with a prior history of HSV-associated acute retinal necrosis.
. 2021 Jul 16;2021:7336488.
doi: 10.1155/2021/7336488. eCollection 2021.
Reactivation of Acute Retinal Necrosis following SARS-CoV-2 Infection
Monica P Gonzalez[SUP] 1 [/SUP], Radames Rios[SUP] 1 [/SUP], Mariella Pappaterra[SUP] 1 [/SUP], Miguel Hernandez[SUP] 2 [/SUP], Allison Toledo[SUP] 3 [/SUP], Carmen Santos[SUP] 1 [/SUP], Andres Emanuelli[SUP] 1 3 [/SUP], Shree K Kurup[SUP] 1 4 [/SUP], Armando L Oliver[SUP] 1 [/SUP]
Affiliations
- PMID: 34336325
- PMCID: PMC8313348
- DOI: 10.1155/2021/7336488
Abstract
Purpose: To report on a case of reactivation of acute retinal necrosis following SARS-CoV-2 infection.
Methods: Observational case report. Observations. A 32-year-old female with a distant history of left retinal detachment secondary to necrotizing herpetic retinitis complained of right-eye vision loss, pain, redness, and photophobia. An ophthalmological examination revealed findings consistent with acute retinal necrosis of the right eye. A polymerase chain reaction (PCR) analysis of the right vitreous was positive for herpes simplex virus type 2 (HSV-2). A coronavirus disease 2019 (COVID-19) screening test using reverse transcriptase- (RT-) PCR was positive for SARS-CoV-2 RNA.
Conclusions: Our case suggests that COVID-19 may cause a latent HSV infection to reactivate, causing contralateral involvement in patients with a prior history of HSV-associated acute retinal necrosis.