tetano
Editor, Senior Moderator
Cell
. 2021 Jan 7;184(1):15-17.
doi: 10.1016/j.cell.2020.12.003. Epub 2020 Dec 17.
A Crisp(r) New Perspective on SARS-CoV-2 Biology
Adam L Bailey[SUP] 1 [/SUP], Michael S Diamond[SUP] 2 [/SUP]
Affiliations
Abstract
Complementary genome-wide CRISPR-Cas9 screens performed by multiple groups reveal new insights into SARS-CoV-2 biology including aspects of viral entry, translation, replication, egress, and the genes regulating these processes. Comparisons with other coronaviruses enhances our understanding of the cellular life cycle of this medically important family of emerging viruses.
Copyright ? 2020 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of Interests M.S.D. is a consultant for Inbios, Vir Biotechnology, NGM Biopharmaceuticals, and the Carnival Corporation and on the Scientific Advisory Boards of Moderna and Immunome. The Diamond laboratory has received unrelated funding support from Moderna, Vir Biotechnology, and Emergent BioSolutions.
. 2021 Jan 7;184(1):15-17.
doi: 10.1016/j.cell.2020.12.003. Epub 2020 Dec 17.
A Crisp(r) New Perspective on SARS-CoV-2 Biology
Adam L Bailey[SUP] 1 [/SUP], Michael S Diamond[SUP] 2 [/SUP]
Affiliations
- PMID: 33338422
- PMCID: PMC7746090
- DOI: 10.1016/j.cell.2020.12.003
Abstract
Complementary genome-wide CRISPR-Cas9 screens performed by multiple groups reveal new insights into SARS-CoV-2 biology including aspects of viral entry, translation, replication, egress, and the genes regulating these processes. Comparisons with other coronaviruses enhances our understanding of the cellular life cycle of this medically important family of emerging viruses.
Copyright ? 2020 Elsevier Inc. All rights reserved.
Conflict of interest statement
Declaration of Interests M.S.D. is a consultant for Inbios, Vir Biotechnology, NGM Biopharmaceuticals, and the Carnival Corporation and on the Scientific Advisory Boards of Moderna and Immunome. The Diamond laboratory has received unrelated funding support from Moderna, Vir Biotechnology, and Emergent BioSolutions.