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Cell Entry of Influenza A Viruses: Sweet Talk between HA and CaV1.2

tetano

Editor, Senior Moderator
Cell Host Microbe. 2018 Jun 13;23(6):697-699. doi: 10.1016/j.chom.2018.05.019.
[h=1]Cell Entry of Influenza A Viruses: Sweet Talk between HA and Ca[SUB]V[/SUB]1.2.[/h] Hoffmann M[SUP]1[/SUP], P?hlmann S[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] Influenza A viruses attach to sialic acids on host cells. In this issue of Cell Host & Microbe, Fujioka et al. (2018) show that binding to a specific sialylated cellular protein facilitates infection: engagement of sialic acids linked to the Ca[SUP]2+[/SUP] channel Ca[SUB]V[/SUB]1.2 induces Ca[SUP]2+[/SUP] oscillations, which promote infectious entry.


PMID: 29902433 DOI: 10.1016/j.chom.2018.05.019
 
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