tetano
Editor, Senior Moderator
Pediatr Int. 2017 Sep 22. doi: 10.1111/ped.13428. [Epub ahead of print]
[h=1]Changes in Trends and Impact of Testing for Influenza in Infants with Fever under 90 Days of Age.[/h] Kim S[SUP]1,[/SUP][SUP]2[/SUP], Moon HM[SUP]1,[/SUP][SUP]2[/SUP], Lee JK[SUP]1[/SUP], Rhie K[SUP]1[/SUP], Yoon KW[SUP]1,[/SUP][SUP]2[/SUP], Choi EH[SUP]1,[/SUP][SUP]3[/SUP], Lee HJ[SUP]1,[/SUP][SUP]3[/SUP], Lee H[SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Infants less than 90 days who present with fever are commonly subject to various invasive procedures due to risk of bacterial infections in this age group. However a great proportion are due to viral infections, including influenza. The aim of this study was to assess the impact of testing influenza in infants < 90 days with fever as well as analyze the subjects' characteristics to identify which infants should be considered for such testing.
[h=4]METHODS:[/h] Clinical characteristics and trends in influenza virus testing and treatment were analyzed among febrile infants <90 days who came to the emergency room and were diagnosed with influenza during 2005 to 2015.
[h=4]RESULTS:[/h] Among 5,347 febrile infants <90 days, 963 (18%) underwent influenza viral study. A total of 114 (11.8%) infants were diagnosed with influenza. The positive rates were up to 67% of the febrile infants during the epidemics. Among them, 83 had a history of family contact. While more than half presented with upper respiratory symptoms, 34% showed only fever without respiratory symptoms. A decrease in antibiotic use and admission rates during the study period among infants diagnosed with influenza was seen (p for trend <0.05).
[h=4]CONCLUSIONS:[/h] During the influenza epidemic season, diagnostic tests for influenza based on a detailed contact history are necessary in assessing the cause of fever. Targeted testing for influenza may lead to a decrease in antibiotic use and admission rates in young infants. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Fever; Infant; Influenza
PMID: 28940983 DOI: 10.1111/ped.13428
[h=1]Changes in Trends and Impact of Testing for Influenza in Infants with Fever under 90 Days of Age.[/h] Kim S[SUP]1,[/SUP][SUP]2[/SUP], Moon HM[SUP]1,[/SUP][SUP]2[/SUP], Lee JK[SUP]1[/SUP], Rhie K[SUP]1[/SUP], Yoon KW[SUP]1,[/SUP][SUP]2[/SUP], Choi EH[SUP]1,[/SUP][SUP]3[/SUP], Lee HJ[SUP]1,[/SUP][SUP]3[/SUP], Lee H[SUP]2,[/SUP][SUP]3[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] Infants less than 90 days who present with fever are commonly subject to various invasive procedures due to risk of bacterial infections in this age group. However a great proportion are due to viral infections, including influenza. The aim of this study was to assess the impact of testing influenza in infants < 90 days with fever as well as analyze the subjects' characteristics to identify which infants should be considered for such testing.
[h=4]METHODS:[/h] Clinical characteristics and trends in influenza virus testing and treatment were analyzed among febrile infants <90 days who came to the emergency room and were diagnosed with influenza during 2005 to 2015.
[h=4]RESULTS:[/h] Among 5,347 febrile infants <90 days, 963 (18%) underwent influenza viral study. A total of 114 (11.8%) infants were diagnosed with influenza. The positive rates were up to 67% of the febrile infants during the epidemics. Among them, 83 had a history of family contact. While more than half presented with upper respiratory symptoms, 34% showed only fever without respiratory symptoms. A decrease in antibiotic use and admission rates during the study period among infants diagnosed with influenza was seen (p for trend <0.05).
[h=4]CONCLUSIONS:[/h] During the influenza epidemic season, diagnostic tests for influenza based on a detailed contact history are necessary in assessing the cause of fever. Targeted testing for influenza may lead to a decrease in antibiotic use and admission rates in young infants. This article is protected by copyright. All rights reserved.
This article is protected by copyright. All rights reserved.
[h=4]KEYWORDS:[/h] Fever; Infant; Influenza
PMID: 28940983 DOI: 10.1111/ped.13428