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Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys

tetano

Editor, Senior Moderator
Influenza Res Treat. 2011;2011:285218. doi: 10.1155/2011/285218. Epub 2010 Dec 30.
Characterization of a Low Pathogenic Avian Influenza Virus (H6N1) Isolated from Turkeys.
Shkoda I, Lapin E, Rosenbluth E, Perk S, Geva Z, Inbar A, Davidson I.
Source

Division of Avian Diseases, Kimron Veterinary Institute, P.O. Box 12, Bet Dagan 50250, Israel.
Abstract

An avian influenza virus (AIV), A/turkey/Israel/09 subtype H6N1, was isolated from turkey poults exhibiting typical pathology associated with AIV infection. The virus was characterized by RT-PCR using AIV subtype-specific primers and by the haemagglutination inhibition test using AIV subtype-specific antisera. The virus has an intravenous pathogenicity index of 0 and possessed a nucleotide sequence at the cleavage site of the hemagglutinin gene, PQIETR*GLF, associated with avian influenza viruses of low pathogenicity. Unlike the two previous H6N2 isolates originating from domestic ducks and mallard, the A/turkey/Israel/09 (H6N1) was isolated from turkeys. The gene sequences of the A/turkey/Israel/09 (H6N1) virus show divergence from the former Israeli H6 isolates.

PMID:
23074655
[PubMed]

http://www.ncbi.nlm.nih.gov/pubmed/23074655
 
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