tetano
Editor, Senior Moderator
Chin J Acad Radiol
. 2021 Mar 7;1-7.
doi: 10.1007/s42058-021-00058-2. Online ahead of print.
The evolution of chest CT findings from admission to follow-up in 30 moderate to severe adult patients with COVID-19 pneumonia
Yunfeng Zhou[SUP] #[/SUP][SUP] 1 [/SUP], Hao Ren[SUP] #[/SUP][SUP] 2 [/SUP], Shuo Wang[SUP] 1 [/SUP], Feng You[SUP] 1 [/SUP], Lei Feng[SUP] 1 [/SUP], Minhong Wang[SUP] 1 [/SUP], Jiangtao Wang[SUP] 2 [/SUP]
Affiliations
Abstract
Objective: To analyze the evolution of chest computed tomography (CT) findings from admission to follow-up in moderate to severe patients with coronavirus disease-19 (COVID-19) pneumonia.
Methods: During December 2019-April 2020, the sequential CT images of 30 patients with COVID-19 pneumonia were retrospectively analyzed from admission to follow-up. The qualitative evolution tendency of lung abnormalities and semi-quantitative CT scores were analyzed for temporal change.
Results: The mean hospitalized period was 24.5 ? 9.6 days (range 6-49 days). The average time from the first, second, third, fourth and follow-up CT examination to the initial symptom onset were 4.2 ? 3.1 days, 10.7 ? 4.4 days, 17.1 ? 3.9 days, 24.6 ? 7.5 days, and 42.4 ? 15.6 days, respectively. During illness day 0-5, groundglass opacity (GGO) was the main pattern. The following illness day 6-11, the main CT pattern was consolidation and reticular pattern. The consolidation and reticular pattern gradually dissipate during illness day 12-23, and the reticular pattern and light GGO increased. When illness day was ? 24 days, the reticular pattern and light GGO gradually decrease until complete dissipation. The highest CT score was at illness day 6-11. Pearson correlation analysis showed that the mean and maximum CT score were not correlated with the length of fever (r = 0.018, p = 0.923 and r = 0.086, p = 0.652) and hospitalization (r = 0.192, p = 0.31 and r = 0.273, p = 0.144).
Conclusions: The dynamic evolution of CT manifestation in moderate to severe COVID-19 pneumonia patients followed a specific pattern over time. During illness day 6-11, the extent of lung abnormalities on chest CT was the most severe.
Supplementary information: The online version contains supplementary material available at 10.1007/s42058-021-00058-2.
Keywords: COVID-19; Evolution; Pneumonia; Tomography; X-ray computed.
. 2021 Mar 7;1-7.
doi: 10.1007/s42058-021-00058-2. Online ahead of print.
The evolution of chest CT findings from admission to follow-up in 30 moderate to severe adult patients with COVID-19 pneumonia
Yunfeng Zhou[SUP] #[/SUP][SUP] 1 [/SUP], Hao Ren[SUP] #[/SUP][SUP] 2 [/SUP], Shuo Wang[SUP] 1 [/SUP], Feng You[SUP] 1 [/SUP], Lei Feng[SUP] 1 [/SUP], Minhong Wang[SUP] 1 [/SUP], Jiangtao Wang[SUP] 2 [/SUP]
Affiliations
- PMID: 33718774
- PMCID: PMC7937430
- DOI: 10.1007/s42058-021-00058-2
Abstract
Objective: To analyze the evolution of chest computed tomography (CT) findings from admission to follow-up in moderate to severe patients with coronavirus disease-19 (COVID-19) pneumonia.
Methods: During December 2019-April 2020, the sequential CT images of 30 patients with COVID-19 pneumonia were retrospectively analyzed from admission to follow-up. The qualitative evolution tendency of lung abnormalities and semi-quantitative CT scores were analyzed for temporal change.
Results: The mean hospitalized period was 24.5 ? 9.6 days (range 6-49 days). The average time from the first, second, third, fourth and follow-up CT examination to the initial symptom onset were 4.2 ? 3.1 days, 10.7 ? 4.4 days, 17.1 ? 3.9 days, 24.6 ? 7.5 days, and 42.4 ? 15.6 days, respectively. During illness day 0-5, groundglass opacity (GGO) was the main pattern. The following illness day 6-11, the main CT pattern was consolidation and reticular pattern. The consolidation and reticular pattern gradually dissipate during illness day 12-23, and the reticular pattern and light GGO increased. When illness day was ? 24 days, the reticular pattern and light GGO gradually decrease until complete dissipation. The highest CT score was at illness day 6-11. Pearson correlation analysis showed that the mean and maximum CT score were not correlated with the length of fever (r = 0.018, p = 0.923 and r = 0.086, p = 0.652) and hospitalization (r = 0.192, p = 0.31 and r = 0.273, p = 0.144).
Conclusions: The dynamic evolution of CT manifestation in moderate to severe COVID-19 pneumonia patients followed a specific pattern over time. During illness day 6-11, the extent of lung abnormalities on chest CT was the most severe.
Supplementary information: The online version contains supplementary material available at 10.1007/s42058-021-00058-2.
Keywords: COVID-19; Evolution; Pneumonia; Tomography; X-ray computed.