tetano
Editor, Senior Moderator
Clin Case Rep
. 2021 May 6;e04154.
doi: 10.1002/ccr3.4154. Online ahead of print.
What was behind the first recognition and characterization of autochthonous SARS-CoV-2 transmission in Italy: The impact on European scenario
Valeria Micheli[SUP] 1 [/SUP], Alessandro Mancon[SUP] 1 [/SUP], Annalisa Malara[SUP] 2 [/SUP], Davide Mileto[SUP] 1 [/SUP], Pier Giorgio Villani[SUP] 2 [/SUP], Alberto Rizzo[SUP] 1 [/SUP], Cristina Pagani[SUP] 1 [/SUP], Omar Alquati[SUP] 2 [/SUP], Maria Rita Gismondo[SUP] 1 [/SUP]
Affiliations
Abstract
An Italian male with no link to China Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) epidemic presented at Emergency Room (ER) with severe respiratory impairment. The RT-PCR on 20 February 2020, nasopharyngeal swab revealed SARS-CoV-2 infection, confirmed with viral culture and sequencing. This was the first identified autochthonous SARS-CoV-2 transmission in Italy, that unveiled global pathogen diffusion. This clinical case highlights an underestimation of SARS-CoV-2 circulation, making initial containment measures unfit to face the real situation and delaying the management of potentially affected SARS-CoV-2 patients.
Keywords: RT‐PCR; SARS‐CoV‐2; pandemic; serology; viral culture.
. 2021 May 6;e04154.
doi: 10.1002/ccr3.4154. Online ahead of print.
What was behind the first recognition and characterization of autochthonous SARS-CoV-2 transmission in Italy: The impact on European scenario
Valeria Micheli[SUP] 1 [/SUP], Alessandro Mancon[SUP] 1 [/SUP], Annalisa Malara[SUP] 2 [/SUP], Davide Mileto[SUP] 1 [/SUP], Pier Giorgio Villani[SUP] 2 [/SUP], Alberto Rizzo[SUP] 1 [/SUP], Cristina Pagani[SUP] 1 [/SUP], Omar Alquati[SUP] 2 [/SUP], Maria Rita Gismondo[SUP] 1 [/SUP]
Affiliations
- PMID: 34178331
- PMCID: PMC8209863
- DOI: 10.1002/ccr3.4154
Abstract
An Italian male with no link to China Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) epidemic presented at Emergency Room (ER) with severe respiratory impairment. The RT-PCR on 20 February 2020, nasopharyngeal swab revealed SARS-CoV-2 infection, confirmed with viral culture and sequencing. This was the first identified autochthonous SARS-CoV-2 transmission in Italy, that unveiled global pathogen diffusion. This clinical case highlights an underestimation of SARS-CoV-2 circulation, making initial containment measures unfit to face the real situation and delaying the management of potentially affected SARS-CoV-2 patients.
Keywords: RT‐PCR; SARS‐CoV‐2; pandemic; serology; viral culture.