tetano
Editor, Senior Moderator
Clin Dermatol
. Mar-Apr 2021;39(2):337-343.
doi: 10.1016/j.clindermatol.2020.11.005. Epub 2020 Nov 26.
A dermatologic perspective on multisystem inflammatory syndrome in children
Fludiona Naka[SUP] 1 [/SUP], Laura Melnick[SUP] 2 [/SUP], Mark Gorelik[SUP] 3 [/SUP], Kimberly D Morel[SUP] 4 [/SUP]
Affiliations
Abstract
As of May 2020, an emerging immune-mediated syndrome primarily affecting children has been detected primarily in Europe and the United States. The incidence of this syndrome appears to mirror the initial infectious assault with a delay of several weeks. This syndrome has been termed "multisystem inflammatory syndrome in children" (MIS-C) and is observed in association with the coronavirus disease 2019. The phenotypes of presentation include several characteristic features, including prolonged fever, skin eruptions, neck stiffness, and gastrointestinal manifestations with pronounced abdominal pain. Shock and organ dysfunction on presentation are frequent but inconsistent, whereas respiratory distress is typically, and notably, absent. We have reviewed the recent published data aiming to better understand MIS-C, with a focus on its mucocutaneous manifestations.
. Mar-Apr 2021;39(2):337-343.
doi: 10.1016/j.clindermatol.2020.11.005. Epub 2020 Nov 26.
A dermatologic perspective on multisystem inflammatory syndrome in children
Fludiona Naka[SUP] 1 [/SUP], Laura Melnick[SUP] 2 [/SUP], Mark Gorelik[SUP] 3 [/SUP], Kimberly D Morel[SUP] 4 [/SUP]
Affiliations
- PMID: 34272033
- DOI: 10.1016/j.clindermatol.2020.11.005
Abstract
As of May 2020, an emerging immune-mediated syndrome primarily affecting children has been detected primarily in Europe and the United States. The incidence of this syndrome appears to mirror the initial infectious assault with a delay of several weeks. This syndrome has been termed "multisystem inflammatory syndrome in children" (MIS-C) and is observed in association with the coronavirus disease 2019. The phenotypes of presentation include several characteristic features, including prolonged fever, skin eruptions, neck stiffness, and gastrointestinal manifestations with pronounced abdominal pain. Shock and organ dysfunction on presentation are frequent but inconsistent, whereas respiratory distress is typically, and notably, absent. We have reviewed the recent published data aiming to better understand MIS-C, with a focus on its mucocutaneous manifestations.