tetano
Editor, Senior Moderator
Clin Exp Dermatol. 2020 May 8. doi: 10.1111/ced.14277. [Epub ahead of print]
Clinical and histological characterization of vesicular COVID-19 rashes: A prospective study in a tertiary care hospital.
Fernandez-Nieto D[SUP]1[/SUP], Ortega-Quijano D[SUP]1[/SUP], Jimenez-Cauhe J[SUP]1[/SUP], Burgos-Blasco P[SUP]1[/SUP], de Perosanz-Lobo D[SUP]1[/SUP], Suarez-Valle A[SUP]1[/SUP], Cortes-Cuevas JL[SUP]2[/SUP], Carretero I[SUP]3[/SUP], Garcia Del Real CM[SUP]3[/SUP], Fernandez-Guarino M[SUP]1[/SUP].
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Abstract
Vesicular skin rashes have been associated to the Coronavirus Disease 2019 (COVID-19), but there is little information about this cutaneous manifestation. We designed a prospective observational study of patients diagnosed with COVID-19 and vesicular lesions. Clinical characterization of skin findings was conducted by dermatologists. When possible, histological analysis and detection of severe acute respiratory coronavirus 2 (SARS-CoV-2) in the content of the vesicles was performed. A total of 24 patients were included. A disseminated pattern was found in 18 patients (75%), and a localized pattern was found in 6 patients (25%). The median duration of the skin rash was of 10 days. Out of all, 19 patients (79.2%) presented the skin rash after the onset of COVID-19 symptoms. Histologic examination in two patients was consistent with viral infection, SARS-CoV-2 was not detected in four patients. This monocentric study shows the clinical characteristics of vesicular skin rashes in COVID-19 patients.
This article is protected by copyright. All rights reserved.
PMID:32384180DOI:10.1111/ced.14277
Clinical and histological characterization of vesicular COVID-19 rashes: A prospective study in a tertiary care hospital.
Fernandez-Nieto D[SUP]1[/SUP], Ortega-Quijano D[SUP]1[/SUP], Jimenez-Cauhe J[SUP]1[/SUP], Burgos-Blasco P[SUP]1[/SUP], de Perosanz-Lobo D[SUP]1[/SUP], Suarez-Valle A[SUP]1[/SUP], Cortes-Cuevas JL[SUP]2[/SUP], Carretero I[SUP]3[/SUP], Garcia Del Real CM[SUP]3[/SUP], Fernandez-Guarino M[SUP]1[/SUP].
Author information
Abstract
Vesicular skin rashes have been associated to the Coronavirus Disease 2019 (COVID-19), but there is little information about this cutaneous manifestation. We designed a prospective observational study of patients diagnosed with COVID-19 and vesicular lesions. Clinical characterization of skin findings was conducted by dermatologists. When possible, histological analysis and detection of severe acute respiratory coronavirus 2 (SARS-CoV-2) in the content of the vesicles was performed. A total of 24 patients were included. A disseminated pattern was found in 18 patients (75%), and a localized pattern was found in 6 patients (25%). The median duration of the skin rash was of 10 days. Out of all, 19 patients (79.2%) presented the skin rash after the onset of COVID-19 symptoms. Histologic examination in two patients was consistent with viral infection, SARS-CoV-2 was not detected in four patients. This monocentric study shows the clinical characteristics of vesicular skin rashes in COVID-19 patients.
This article is protected by copyright. All rights reserved.
PMID:32384180DOI:10.1111/ced.14277