tetano
Editor, Senior Moderator
Clin Exp Dermatol
. 2022 May 23.
doi: 10.1111/ced.15271. Online ahead of print.
Mucocutaneous manifestations of COVID-19 related multisystem inflammatory syndrome in adults (MIS-A): an update
Abheek Sil[SUP] 1 [/SUP], Anupam Das[SUP] 2 [/SUP], Debatri Datta[SUP] 3 [/SUP]
Affiliations
Abstract
Multisystem inflammatory syndrome in adults (MIS-A) is an inflammatory condition affecting multiple extrapulmonary organ systems (cardiac, gastrointestinal tract, dermatological and/or neurological), attributed to a post-infectious and atypical complication occurring weeks to months after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The diagnosis is primarily based on findings encompassing persistent fever, elevated inflammatory markers, multi-organ involvement, and a temporal relationship with coronavirus 2019 infection. The existing literature on MIS-A, although growing, is limited to case reports and small cases series. It is imperative that dermatologists be aware of this entity and aid the critical care team to ensure timely diagnosis and early therapeutic intervention. In this review, we concisely highlight the varied presentations, pathogenesis, and treatment options in MIS-A.
. 2022 May 23.
doi: 10.1111/ced.15271. Online ahead of print.
Mucocutaneous manifestations of COVID-19 related multisystem inflammatory syndrome in adults (MIS-A): an update
Abheek Sil[SUP] 1 [/SUP], Anupam Das[SUP] 2 [/SUP], Debatri Datta[SUP] 3 [/SUP]
Affiliations
- PMID: 35603763
- DOI: 10.1111/ced.15271
Abstract
Multisystem inflammatory syndrome in adults (MIS-A) is an inflammatory condition affecting multiple extrapulmonary organ systems (cardiac, gastrointestinal tract, dermatological and/or neurological), attributed to a post-infectious and atypical complication occurring weeks to months after infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The diagnosis is primarily based on findings encompassing persistent fever, elevated inflammatory markers, multi-organ involvement, and a temporal relationship with coronavirus 2019 infection. The existing literature on MIS-A, although growing, is limited to case reports and small cases series. It is imperative that dermatologists be aware of this entity and aid the critical care team to ensure timely diagnosis and early therapeutic intervention. In this review, we concisely highlight the varied presentations, pathogenesis, and treatment options in MIS-A.