tetano
Editor, Senior Moderator
Clin Infect Dis
. 2020 Jun 16;ciaa759.
doi: 10.1093/cid/ciaa759. Online ahead of print.
Performance of Oropharyngeal Swab Testing Compared to Nasopharyngeal Swab Testing for Diagnosis of COVID-19 -United States, January-February 2020
Monita R Patel[SUP] 1 [/SUP], Darin Carroll[SUP] 1 [/SUP], Emily Ussery[SUP] 1 [/SUP], Hilary Whitham[SUP] 1 [/SUP], Christopher A Elkins[SUP] 1 [/SUP], Judith Noble-Wang[SUP] 1 [/SUP], James Kamile Rasheed[SUP] 1 [/SUP], Xioayan Lu[SUP] 1 [/SUP], Stephen Lindstrom[SUP] 1 [/SUP], Virginia Bowen[SUP] 1 [/SUP], Jessica Waller[SUP] 1 [/SUP], Gregory Armstrong[SUP] 1 [/SUP], Susan Gerber[SUP] 1 [/SUP], John T Brooks[SUP] 1 [/SUP]
Affiliations
Abstract
Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days since illness onset, CDC real-time RT-PCR SARS-CoV-2 assay diagnostic results were 95.2% concordant. However, NP swab Ct values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect amount of SARS-CoV-2.
Keywords: SARS-CoV-2; coronavirus; cycle threshold values; nasopharyngeal; oropharyngeal; testing.
. 2020 Jun 16;ciaa759.
doi: 10.1093/cid/ciaa759. Online ahead of print.
Performance of Oropharyngeal Swab Testing Compared to Nasopharyngeal Swab Testing for Diagnosis of COVID-19 -United States, January-February 2020
Monita R Patel[SUP] 1 [/SUP], Darin Carroll[SUP] 1 [/SUP], Emily Ussery[SUP] 1 [/SUP], Hilary Whitham[SUP] 1 [/SUP], Christopher A Elkins[SUP] 1 [/SUP], Judith Noble-Wang[SUP] 1 [/SUP], James Kamile Rasheed[SUP] 1 [/SUP], Xioayan Lu[SUP] 1 [/SUP], Stephen Lindstrom[SUP] 1 [/SUP], Virginia Bowen[SUP] 1 [/SUP], Jessica Waller[SUP] 1 [/SUP], Gregory Armstrong[SUP] 1 [/SUP], Susan Gerber[SUP] 1 [/SUP], John T Brooks[SUP] 1 [/SUP]
Affiliations
- PMID: 32548635
- DOI: 10.1093/cid/ciaa759
Abstract
Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days since illness onset, CDC real-time RT-PCR SARS-CoV-2 assay diagnostic results were 95.2% concordant. However, NP swab Ct values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect amount of SARS-CoV-2.
Keywords: SARS-CoV-2; coronavirus; cycle threshold values; nasopharyngeal; oropharyngeal; testing.