tetano
Editor, Senior Moderator
Clin Infect Dis
. 2021 Feb 1;72(3):403-410.
doi: 10.1093/cid/ciaa759.
Performance of Oropharyngeal Swab Testing Compared With Nasopharyngeal Swab Testing for Diagnosis of Coronavirus Disease 2019-United States, January 2020-February 2020
Monita R Patel[SUP] 1 [/SUP], Darin Carroll[SUP] 1 [/SUP], Emily Ussery[SUP] 1 [/SUP], Hilary Whitham[SUP] 1 [/SUP], Christopher A Elkins[SUP] 1 [/SUP], Judith Noble-Wang[SUP] 1 [/SUP], James Kamile Rasheed[SUP] 1 [/SUP], Xiaoyan Lu[SUP] 1 [/SUP], Stephen Lindstrom[SUP] 1 [/SUP], Virginia Bowen[SUP] 1 [/SUP], Jessica Waller[SUP] 1 [/SUP], Gregory Armstrong[SUP] 1 [/SUP], Susan Gerber[SUP] 1 [/SUP], John T Brooks[SUP] 1 [/SUP]
Affiliations
Abstract
Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days after illness onset, Real-Time Reverse Transcriptase Polymerase Chain Reaction assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 RT-PCR) diagnostic results were 95.2% concordant. However, NP swab cycle threshold values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect the amount of SARS-CoV-2.
Keywords: SARS-CoV-2; coronavirus; nasopharyngeal; oropharyngeal; testing.
. 2021 Feb 1;72(3):403-410.
doi: 10.1093/cid/ciaa759.
Performance of Oropharyngeal Swab Testing Compared With Nasopharyngeal Swab Testing for Diagnosis of Coronavirus Disease 2019-United States, January 2020-February 2020
Monita R Patel[SUP] 1 [/SUP], Darin Carroll[SUP] 1 [/SUP], Emily Ussery[SUP] 1 [/SUP], Hilary Whitham[SUP] 1 [/SUP], Christopher A Elkins[SUP] 1 [/SUP], Judith Noble-Wang[SUP] 1 [/SUP], James Kamile Rasheed[SUP] 1 [/SUP], Xiaoyan Lu[SUP] 1 [/SUP], Stephen Lindstrom[SUP] 1 [/SUP], Virginia Bowen[SUP] 1 [/SUP], Jessica Waller[SUP] 1 [/SUP], Gregory Armstrong[SUP] 1 [/SUP], Susan Gerber[SUP] 1 [/SUP], John T Brooks[SUP] 1 [/SUP]
Affiliations
- PMID: 33527126
- DOI: 10.1093/cid/ciaa759
Abstract
Among 146 nasopharyngeal (NP) and oropharyngeal (OP) swab pairs collected ≤7 days after illness onset, Real-Time Reverse Transcriptase Polymerase Chain Reaction assay for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 RT-PCR) diagnostic results were 95.2% concordant. However, NP swab cycle threshold values were lower (indicating more virus) in 66.7% of concordant-positive pairs, suggesting NP swabs may more accurately detect the amount of SARS-CoV-2.
Keywords: SARS-CoV-2; coronavirus; nasopharyngeal; oropharyngeal; testing.