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Clin Infect Dis . The first known human death after infection with the avian influenza (A/H3N8) virus: Guangdong Province, China, March 2023

tetano

Editor, Senior Moderator
Clin Infect Dis


. 2023 Aug 9;ciad462.
doi: 10.1093/cid/ciad462. Online ahead of print. The first known human death after infection with the avian influenza (A/H3N8) virus: Guangdong Province, China, March 2023

Yali Zhuang[SUP] 1 [/SUP], Man Wang[SUP] 2 [/SUP], Lijun Liang[SUP] 1 [/SUP], Yunxia Mao[SUP] 2 [/SUP], Kaibin Wang[SUP] 3 4 [/SUP], Shuhuan Yang[SUP] 2 [/SUP], Aiping Deng[SUP] 1 [/SUP], Kewen Zeng[SUP] 5 [/SUP], Yingtao Zhang[SUP] 1 [/SUP], Guanting Zhang[SUP] 1 [/SUP], Min Kang[SUP] 1 [/SUP], Baisheng Li[SUP] 1 [/SUP], Meng Zhang[SUP] 1 [/SUP], Shinan Ye[SUP] 2 [/SUP]



Affiliations
Abstract

We reported a case of human infection with the H3N8 avian influenza virus, who had multiple myeloma and died of severe infection. Genome analysis showed multiple gene mutations and reassortments without mammalian-adaptive mutations. This report suggested that avian influenza (A/H3N8) virus infection could be lethal for person who were immunocompromised.

Keywords: A/H3N8; Avian Influenza; Fatal Case; Human Infection; Immunodeficiency.

 
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