tetano
Editor, Senior Moderator
Clin Lymphoma Myeloma Leuk
. 2020 Jun 25;S2152-2650(20)30312-8.
doi: 10.1016/j.clml.2020.06.014. Online ahead of print.
Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient on Ruxolitinib
Francine M Foss[SUP] 1 [/SUP], Ami Rubinowitz[SUP] 2 [/SUP], Marie L Landry[SUP] 3 [/SUP], Iris Isufi[SUP] 4 [/SUP], Lohith Gowda[SUP] 4 [/SUP], Stuart Seropian[SUP] 4 [/SUP], Sarah Perreault[SUP] 5 [/SUP], Sheela V Shenoi[SUP] 6 [/SUP]
Affiliations
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has a high death rate in patients with comorbidities or in an immunocompromised state. We report a mild and attenuated SARS CoV-2 infection in a patient who is 17 months post stem cell transplantation and maintained on the JAK/STAT inhibitor ruxolitinib, a proposed novel therapy for SARS CoV-2 pneumonia.
Keywords: Allogeneic stem cell transplantation; COVID-19; Graft-versus-host disease; Immunocompromised; JAK inhibitor.
. 2020 Jun 25;S2152-2650(20)30312-8.
doi: 10.1016/j.clml.2020.06.014. Online ahead of print.
Attenuated Novel SARS Coronavirus 2 Infection in an Allogeneic Hematopoietic Stem Cell Transplant Patient on Ruxolitinib
Francine M Foss[SUP] 1 [/SUP], Ami Rubinowitz[SUP] 2 [/SUP], Marie L Landry[SUP] 3 [/SUP], Iris Isufi[SUP] 4 [/SUP], Lohith Gowda[SUP] 4 [/SUP], Stuart Seropian[SUP] 4 [/SUP], Sarah Perreault[SUP] 5 [/SUP], Sheela V Shenoi[SUP] 6 [/SUP]
Affiliations
- PMID: 32727701
- DOI: 10.1016/j.clml.2020.06.014
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS CoV-2) has a high death rate in patients with comorbidities or in an immunocompromised state. We report a mild and attenuated SARS CoV-2 infection in a patient who is 17 months post stem cell transplantation and maintained on the JAK/STAT inhibitor ruxolitinib, a proposed novel therapy for SARS CoV-2 pneumonia.
Keywords: Allogeneic stem cell transplantation; COVID-19; Graft-versus-host disease; Immunocompromised; JAK inhibitor.