tetano
Editor, Senior Moderator
Clin Neurol Neurosurg
. 2022 May 19;218:107304.
doi: 10.1016/j.clineuro.2022.107304. Online ahead of print.
Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine
Hussein A Algahtani[SUP] 1 [/SUP], Bader H Shirah[SUP] 2 [/SUP], Emad Alwafi[SUP] 3 [/SUP]
Affiliations
Abstract
The coronavirus disease of 2019 (COVID-19) pandemic is caused by a novel coronavirus SARS-Cov-2. Four major vaccine types are being used to fight against this deadly pandemic and save precious human lives. All types of vaccines have been associated with a risk of neurological complications ranging from mild to severe. Cervical dystonia occurring after a COVID-19 vaccine was not previously reported in the literature. In this article, we describe a case of acute cervical dystonia occurring after the first dose of the BNT162b2 COVID-19 vaccine. We attribute the occurrence of cervical dystonia to the vaccine due to the temporal relationship. This report adds to the literature a possible rare side effect of a COVID-19 vaccine and contributes to the limited literature on potential neurological side effects of mRNA-based vaccines. The likely mechanism is autoimmune. Further research is needed to probe and study the exact mechanism.
Keywords: BNT162b2 mRNA; COVID-19; Cervical Dystonia; Saudi Arabia; Vaccine.
. 2022 May 19;218:107304.
doi: 10.1016/j.clineuro.2022.107304. Online ahead of print.
Acute cervical dystonia following the BNT162b2 mRNA COVID-19 vaccine
Hussein A Algahtani[SUP] 1 [/SUP], Bader H Shirah[SUP] 2 [/SUP], Emad Alwafi[SUP] 3 [/SUP]
Affiliations
- PMID: 35605509
- DOI: 10.1016/j.clineuro.2022.107304
Abstract
The coronavirus disease of 2019 (COVID-19) pandemic is caused by a novel coronavirus SARS-Cov-2. Four major vaccine types are being used to fight against this deadly pandemic and save precious human lives. All types of vaccines have been associated with a risk of neurological complications ranging from mild to severe. Cervical dystonia occurring after a COVID-19 vaccine was not previously reported in the literature. In this article, we describe a case of acute cervical dystonia occurring after the first dose of the BNT162b2 COVID-19 vaccine. We attribute the occurrence of cervical dystonia to the vaccine due to the temporal relationship. This report adds to the literature a possible rare side effect of a COVID-19 vaccine and contributes to the limited literature on potential neurological side effects of mRNA-based vaccines. The likely mechanism is autoimmune. Further research is needed to probe and study the exact mechanism.
Keywords: BNT162b2 mRNA; COVID-19; Cervical Dystonia; Saudi Arabia; Vaccine.