tetano
Editor, Senior Moderator
Rev Med Chil. 2011 Mar;139(3):321-6. Epub 2011 Aug 25.
[Clinical impact of pandemic influenza A H1N1 in a Chilean regional hospital].
[Article in Spanish]
Riquelme O R, Riquelme O M, Rioseco Z ML, Inzunza P C, Contreras G C, G?mez V Y, Riquelme D J.
Source
Enfermedades Respiratorias, Servicio de Medicina, Hospital de Puerto Montt, Puerto Montt, Chile.
Abstract
Background: Pandemic flu (H1N1 ) strongly affected southern Chile during2009. Aim: To report the logistic and organizational changes implemented at a regional hospital to face the pandemic. Material and Methods: All patients with flu like disease that were hospitalized, were prospectively enrolled at the Puerto Montt hospital. A nasopharyngeal aspirate was obtained in all for influenza virus A and B direct immunofluorescence and polymerase chain reaction (PCR). All epidemiological and clinical data of patients were recorded. Results: Between May 29 and July 7, 2009, 184 adults were admitted to the hospital and in 117patients aged 41 ? 18 years (56% females ), direct immunofluorescence was positive for influenza. In 67 of these patients PCR did not confirm the disease. These unconfirmed patients had a mean age of 49 ? 19 years (p < 0.01, compared with confirmed cases) and had a lower frequency of fever, rhinorrhea and chills. No significant differences in the incidence of community acquired pneumonia or chest X ray findings were observed between confirmed and unconfirmed cases. Hospital stay was over 15 days in 14% of confirmed cases and 5% of unconfirmed cases (p = 0.03). Fifteen patients, aged 53 ? 18 years, died. Conclusions: Low sensibility of direct immunofluorescence and delay in obtaining PCR confirmation of influenza posed a problem for the management of these patients.
PMID:
21879163
[PubMed - in process]
Free full text
http://www.ncbi.nlm.nih.gov/pubmed/21879163
[Clinical impact of pandemic influenza A H1N1 in a Chilean regional hospital].
[Article in Spanish]
Riquelme O R, Riquelme O M, Rioseco Z ML, Inzunza P C, Contreras G C, G?mez V Y, Riquelme D J.
Source
Enfermedades Respiratorias, Servicio de Medicina, Hospital de Puerto Montt, Puerto Montt, Chile.
Abstract
Background: Pandemic flu (H1N1 ) strongly affected southern Chile during2009. Aim: To report the logistic and organizational changes implemented at a regional hospital to face the pandemic. Material and Methods: All patients with flu like disease that were hospitalized, were prospectively enrolled at the Puerto Montt hospital. A nasopharyngeal aspirate was obtained in all for influenza virus A and B direct immunofluorescence and polymerase chain reaction (PCR). All epidemiological and clinical data of patients were recorded. Results: Between May 29 and July 7, 2009, 184 adults were admitted to the hospital and in 117patients aged 41 ? 18 years (56% females ), direct immunofluorescence was positive for influenza. In 67 of these patients PCR did not confirm the disease. These unconfirmed patients had a mean age of 49 ? 19 years (p < 0.01, compared with confirmed cases) and had a lower frequency of fever, rhinorrhea and chills. No significant differences in the incidence of community acquired pneumonia or chest X ray findings were observed between confirmed and unconfirmed cases. Hospital stay was over 15 days in 14% of confirmed cases and 5% of unconfirmed cases (p = 0.03). Fifteen patients, aged 53 ? 18 years, died. Conclusions: Low sensibility of direct immunofluorescence and delay in obtaining PCR confirmation of influenza posed a problem for the management of these patients.
PMID:
21879163
[PubMed - in process]
Free full text
http://www.ncbi.nlm.nih.gov/pubmed/21879163