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Comparison of the Clinical Features of Children Hospitalized With Pandemic 2009 A:H1N1 and Seasonal Influenza

tetano

Editor, Senior Moderator
Clin Pediatr (Phila). 2011 Apr;50(4):348-54.
Comparison of the Clinical Features of Children Hospitalized With Pandemic 2009 A:H1N1 and Seasonal Influenza.

Ostovar GA, Rubin LG, Rajan S, Sood SK, Kohn N.

North Shore-Long Island Jewish Health System, New Hyde Park, NY, USA, gostovar@nshs.edu.
Abstract

Introduction: We compared the demographics, clinical presentation, course and outcome of children hospitalized with pandemic A:H1N1 and seasonal influenza. Methods: Sixty seven patients hospitalized from April 1st through August 31st 2009 with pandemic A:H1N1 influenza were enrolled. Two seasonal influenza cohorts were identified: 38 inpatients from January 1st 2004 through March 31st 2009, diagnosed by viral culture or direct fluorescent antibody testing; and 42 inpatients from January 1st 2007 through December 31st 2008 diagnosed via a rapid test. The two seasonal cohorts were not significantly different and were combined. Results: Patients with pandemic influenza were older (median age 6.5 years versus 1.3 years, P <.0001); were more often black (46% versus 23%, P <.0002); more frequently had an underlying condition (72% versus 49% P <.0049); and more often had wheezing (57% versus 16%, P <.0001). Conclusion: There was no significant difference between the groups in measures of severity during hospitalization.

PMID: 21436149 [PubMed - in process]

http://www.ncbi.nlm.nih.gov/pubmed/21436149
 
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