tetano
Editor, Senior Moderator
Vaccine. 2015 Apr 25. pii: S0264-410X(15)00527-7. doi: 10.1016/j.vaccine.2015.04.063. [Epub ahead of print]
[h=1]Concurrent and cross-season protection of inactivated influenza vaccine against A(H1N1)pdm09 illness among young children: 2012-2013 case-control evaluation of influenza vaccine effectiveness.[/h] Fu C[SUP]1[/SUP], Xu J[SUP]2[/SUP], Lin J[SUP]3[/SUP], Wang M[SUP]2[/SUP], Li K[SUP]2[/SUP], Ge J[SUP]3[/SUP], Thompson MG[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In 2012-2013, we examined 1729 laboratory-confirmed A(H1N1)pdm09 influenza cases matched 1:1 with healthy controls and estimated influenza vaccine effectiveness (VE) for trivalent inactivated influenza vaccine (IIV3) to be 67% (95% confidence interval=58-74%) for ages 8 months to 6 years old. Among children aged 8-35 months old, VE for fully vaccinated children (73%, 60-81%) was significantly higher than VE for partially vaccinated children (55%, 33-70%). Significant cross-season protection from prior IIV3 was noted, including VE of 31% (8-48%) from IIV3 received in 2010-2011 against influenza illness in 2012--2013 without subsequent boosting doses.
Published by Elsevier Ltd.
[h=4]KEYWORDS:[/h] A(H1N1)pdm09 influenza; Children; Influenza vaccines; Prior vaccination; Vaccine effectiveness
PMID: 25921713 [PubMed - as supplied by publisher]
[h=1]Concurrent and cross-season protection of inactivated influenza vaccine against A(H1N1)pdm09 illness among young children: 2012-2013 case-control evaluation of influenza vaccine effectiveness.[/h] Fu C[SUP]1[/SUP], Xu J[SUP]2[/SUP], Lin J[SUP]3[/SUP], Wang M[SUP]2[/SUP], Li K[SUP]2[/SUP], Ge J[SUP]3[/SUP], Thompson MG[SUP]4[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] In 2012-2013, we examined 1729 laboratory-confirmed A(H1N1)pdm09 influenza cases matched 1:1 with healthy controls and estimated influenza vaccine effectiveness (VE) for trivalent inactivated influenza vaccine (IIV3) to be 67% (95% confidence interval=58-74%) for ages 8 months to 6 years old. Among children aged 8-35 months old, VE for fully vaccinated children (73%, 60-81%) was significantly higher than VE for partially vaccinated children (55%, 33-70%). Significant cross-season protection from prior IIV3 was noted, including VE of 31% (8-48%) from IIV3 received in 2010-2011 against influenza illness in 2012--2013 without subsequent boosting doses.
Published by Elsevier Ltd.
[h=4]KEYWORDS:[/h] A(H1N1)pdm09 influenza; Children; Influenza vaccines; Prior vaccination; Vaccine effectiveness
PMID: 25921713 [PubMed - as supplied by publisher]