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Confirmation of Avian Influenza H7N2 Infection in Wales

Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Commonground-
It could be, but it reads like a separate report. It was mentioned in another article I came across....you'd think the report would point that information out. I'll try and find the other instance.

Hawkeye, could it be this child in Post #48:

A dozen schoolchildren and two members of staff at Ysgol Henllan primary school near the Corwen farm have been offered courses of anti-flu drug Tamiflu after one of the pupils is thought to have contracted the virus.

The child lives at a neighbouring property to the farm and the staff and pupils receiving treatment had all been in close proximity to the youngster.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

here's the other instance where I ask the same question. If I had time I would try and map the hospitals.
http://www.flutrackers.com/forum/showpost.php?p=83018&postcount=1

Staff and patients at a hospital are being treated with anti-avian flu drugs after it emerged a health worker may have been infected with the virus.

Almost 80 people at Glan Clwyd hospital in North Wales have received the Tamiflu drug as a precaution.

The move comes after it was confirmed a worker at the hospital was being treated for the H7 flu virus.

Health officials are contacting a further 69 people at Gwynedd hospital after a former patient suffered symptoms.

On Monday, schoolchildren and staff at Ysgol Henllan primary school near the Corwen farm were offered courses of anti-flu drug Tamiflu after a pupil fell ill.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Thanks everyone. Hawkeye - great maps!
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

the 2 hospitals are approx 35 miles apart hawkeye.







start:Bangor, LL57 2via:end:Rhyl, LL18 1total distance: 34.79 miles (55.99 km)
est. duration: 43 minute(s)
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Hawkeye - I see what you mean. Wish they would use names. I'd be happy with initials.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

School and hospitals

schoolswebdirectory.co.uk<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" /><o:p></o:p>
School Information <o:p></o:p>
Our Ref No : 22133 <o:p></o:p>
<o:p></o:p>
School: Ysgol Henllan <o:p></o:p>
Street: <?xml:namespace prefix = st1 ns = "urn:schemas-microsoft-com:office:smarttags" /><st1:Street w:st="on"><st1:address w:st="on">Denbigh Street</st1:address></st1:Street> <o:p></o:p>
Town: Denbigh <o:p></o:p>
County: Denbighshire <o:p></o:p>
Postcode: LL16 5AW<o:p></o:p>
<o:p> </o:p>
-------------------------------------------<o:p></o:p>
<st1:place w:st="on"><st1:PlaceName w:st="on">Glan</st1:PlaceName> <st1:PlaceName w:st="on">Clwyd</st1:PlaceName> <st1:PlaceType w:st="on">Hospital</st1:PlaceType></st1:place>, <st1:Street w:st="on"><st1:address w:st="on">Sarn Lane</st1:address></st1:Street>, Rhyl, Denbighshire<o:p></o:p>
Postcode LL18 5UJ Telephone <o:p></o:p>
01745 583910 <o:p></o:p>
Website <o:p></o:p>
http://www.cd-tr.wales.nhs.uk/ <o:p></o:p>
<o:p> </o:p>
---------------------------<o:p></o:p>
HOSPITAL INFORMATION:<o:p></o:p>
Ysbyty Gwynedd<o:p></o:p>
Penrhosgarnedd,<o:p></o:p>
<st1:City w:st="on"><st1:place w:st="on">Bangor</st1:place></st1:City>,<o:p></o:p>
Gwynedd.<o:p></o:p>
LL57 2PW.<o:p></o:p>
Tel: 01248 384384<o:p></o:p>
(Trust Headquarters)<o:p></o:p>
<o:p> </o:p>
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

hat-tip deadandalive

quite a good video at http://news.bbc.co.uk/1/hi/wales/6701927.stm father of the girl in wales saying she and is wife negative he is still possitive. Look here:

VIDEO AND AUDIO NEWS
"The tests apparently are negative but they are treating her as a positive case"
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

In the UK the fear of panic still appears to outweigh the realisation of the need for containment.

None of these stories have been front page news in the press in the UK, and stories have been buried within the papers with barely a mention. This is particulary worrisome for general awareness in the UK and to trace persons who may have been in contact, and to encourage awareness amongst poultry owners to report dying or ill chickens. Given the infective source traces back to a market, and bearing in mind the pattern of spread during the foot and mouth outbreak, this does not bode well. I cannot imagine that this was the only chicken infected, and wonder just how widespread this might be, and how many other human contacts there are to infected poultry.

International pressure needs to be brought to bear on UK authorities to be far more public about the problem, if there is to be any hope of containing it. Urgently.

Thanks for the maps hawkeye.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

i dont want to stray too far from the story vibrant,but the whole country at the moent is more concerend about the litle girl thats missing,the media are turning it into a circus,perhaps its time they concentrated on other stories as well.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

hat-tip deadandalive

quite a good video at http://news.bbc.co.uk/1/hi/wales/6701927.stm father of the girl in wales saying she and is wife negative he is still possitive. Look here:

VIDEO AND AUDIO NEWS
"The tests apparently are negative but they are treating her as a positive case"
The audio makers it clear that the test results do not really identify who was and who wasn't infected. It is likely that all three family members were infected, since both parents tested positive at least once, and the daughter has symptoms that respond to Tamiflu (and the daughter's classmates and teachers ahve been offered Tamiflu).

It seems likely that the true number of infectins will not be known until convelescent serum is tested for H7 antibodies.

The failure to get conclusive results with the PCR test, creates significant treatment, prevention, and monitoring issues.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Dr Niman, much like what we are going thru in Indonesia, with the Tamiflu.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Dr Niman, much like what we are going thru in Indonesia, with the Tamiflu.
The link no longer accesses the video. I was able to view it twice, but didn't get a chance to take notes and get the names of the student or her parents. Was the student Megan Evans?
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

yes, Meagan Evans. I'll see what I can do to get another link.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

yes, Meagan Evans. I'll see what I can do to get another link.
Link is working again. I believ the report also indicated a clasemate had symptoms also, but tested negative and took Tamiflu. Sounds like there is little lab support to definitively say how was and wasn't infected.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Dr. Niman,
The fathers name is Ean Evans. the 10 yrs old who had flu-like symptoms and tested neg., and is on tamiflu is Josh Ludewig, mother is Marion. No reference to Meagan's mothers name.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Commentary

H7N2 Familial Cluster in Wales England

Recombinomics Commentary
May 29, 2007


A dozen schoolchildren and two members of staff at Ysgol Henllan primary school near the Corwen farm have been offered courses of anti-flu drug Tamiflu after one of the pupils is thought to have contracted the virus.

The child lives at a neighbouring property to the farm and the staff and pupils receiving treatment had all been in close proximity to the youngster.

The above comments on the H7N2 outbreak fail to capture the confusion regarding the testing of patients and contacts. The student described above, Megan Evans, had symptoms and responded to treatment. An interview with her father, Ian Evans, indicated he was positive and his wife was initially positive, but subsequently tested negative. Moreover, one of Megan's classmates had symptoms, but tested negative.

Thus, in the Evans family, three members either tested positive or had symptoms, suggesting H7N2 was efficiently transmitted from human-to-human. The number of human cases is remarkably high, since only 15 chickens were bought at the market.

The owners of the farm also initially had symptoms, although they too tested negative. A better picture of human H7N2 infections will emerge when convalescent serum is tested for H7 antibodies. However, at this time, the human-to-human spread appears to be quite efficient, comments by government officials notwithstanding.

The inability to reliably test patients with symptoms, or reliably track contacts, is a major cause for concern. Although these initial cases are mild, extensive passage of H7N2 through a na?ve human population can lead to genetic alterations that could affect virulence. These concerns are compounded by the inability of the surveillance program to detect H5N1 or H7 in live wild birds and the potential for dual infections in a number of hosts.


.
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Date: Tue 20 May 2007
Source: BBC News online a.m. Tue 29 May 2007 [edited]
<http://news.bbc.co.uk/1/hi/wales/6699595.stm>


<TABLE cellSpacing=0 cellPadding=0 width=556 border=0 valign="top"><TBODY><TR vAlign=top><TD vAlign=top width=2 bgColor=white> </TD><TD vAlign=top width=554><!-- start: main content --><TABLE cellSpacing=0 cellPadding=0 width="100%" summary="" border=0><TBODY><TR><TD align=left><INPUT onclick="javascript:this.disabled=true; doSubmit('Back');" type=button value=Back></TD></TR></TBODY></TABLE><TABLE summary=""><TBODY><TR><TD noWrap align=right>Archive Number</TD><TD noWrap align=left>20070529.1734</TD></TR><TR><TD noWrap align=right>Published Date</TD><TD noWrap align=left>29-MAY-2007</TD></TR><TR><TD noWrap align=right>Subject</TD><TD noWrap align=left>PRO/AH/EDR> Avian influenza H7N2, human - UK (05), WHO</TD></TR></TBODY></TABLE>
AVIAN INFLUENZA H7N2, HUMAN - UK (05), WHO</PRE></TD></TR></TBODY></TABLE></P>Avian flu contacts 'identified'
-------------------------------
Teachers and pupils at Ysgol Henllan have been given treatment [for
avian influenza]. Health officials say they have identified all the
people who came into close contact with an outbreak of avian flu at a
smallholding in north Wales. The number of people found to have had
contact with the disease rose over the weekend to 142, of which 12
are being treated as being positive for bird flu. The mild H7N2
strain of bird flu was first found last week [20-26 May 2007] among
chickens at a farm near Corwen, Conwy.

Children at a Denbighshire school are being offered anti-viral
medication. A year-5 pupil at Ysgol Henllan suspected of contracting
the virus has been linked to the smallholding. A dozen children, aged
9 and 10, and 2 teachers at the school are being given Tamiflu
treatments as a precaution. The National Public Health Service of
Wales has said a total of 142 people have had either direct or
indirect contact with the virus, which is not the virulent H5N1
strain of avian flu. A total of 12 people are being treated as
"positive," but no one is seriously ill.

Of the 142 to come into contact with the virus, 47 came into contact
"in the household setting," 14 in the school and 81 in "the workplace
setting." Health officials held a meeting for concerned parents at
the school on Monday evening [28 May 2007], in which it was stressed
the risk of anyone contracting the virus is very small.

The National Public Health Service of Wales's director for north
Wales, Andrew Jones, said it was "reassuring" so few people had
reported symptoms. He said, "We are treating 12 cases as positive. We
always approach schools in a precautionary way. We are advising them
that the risk to the population is low and that avian flu is a
disease of birds. It would be very unusual for it to spread from
person to person."

Hugh Pennington, a microbiologist and bird flu expert from Aberdeen
University, added, "You have to be in quite close contact with
infected birds to get infected. It doesn't spread from one infected
person to another. It's still a bird virus; someone infected isn't
going to cause any more human cases."

The 1st confirmed case involved a smallholding at Llanfihangel Glyn
Myfyr, Conwy. Owners Tony Williams and Barbara Cowling, who have
tested negative for the virus, called in a vet after their Rhode
Island Red chickens began to die. They bought the chickens at
Chelford Market at Macclesfield, Cheshire, some 70 miles (112 km)
away, on 7 May [2007]. A total of 30 chickens from the smallholding
have now been slaughtered after 15 birds died.

The 2nd possible case emerged on Saturday [26 May 2007] about 35
miles (56 km) away, at a farm on the outskirts of Efailnewydd, near
Pwllheli. It has also been linked to the market.

******
[2]
Date: Tue 29 May 2007
Source: BBC News, online, p.m. Tue 29 May 2007 [edited]
<http://news.bbc.co.uk/1/hi/wales/6701927.stm>


Bird flu checks reach hospitals
-------------------------------
Hospital patients and staff are being offered anti-viral treatment by
health officials fighting a bird flu outbreak in north Wales. Nearly
80 people at Ysbyty Glan Clwyd at Bodelwyddan are being offered
Tamiflu because of contact with a health worker who is being treated
for the H7 virus. About another 70 patients and staff at Ysbyty
Gwynedd in Bangor are being contacted to see that they are well.

A total of 12 people with flu-like symptoms or conjunctivitis have
been identified. The National Public Health Service for Wales (NPHS)
stressed that no one has been seriously ill and the risk to the
health of the general public is low. So far the service has found a
total of 221 people who may have come into contact with the virus,
which is not as serious as the H5NI strand of the disease.

History of outbreak:
24 May [2007]: The 1st outbreak at Llanfihangel Glyn Myfyr, Conwy; 45
chickens slaughtered but farms test negative for virus.
26 May: The 2nd possible outbreak at farm at Efailnewydd, near
Pwllheli; no test results yet.
29 May: A total of 221 may have had contact with bird flu; 36 in
"household setting," 14 in school, 171 in workplace.

The 1st confirmed case of the avian flu was confirmed last Thursday
[24 May 2007] among chickens on a smallholding near Corwen in
Denbighshire. The Rhode Island chickens 1st affected were bought at a
Chelford Market in Macclesfield, Cheshire on 7 May. On Saturday [26
May 2007] a 2nd possible case emerged at a farm on the outskirts of
Pwllheli although results of tests on birds there have not been finalised.

Some year-5 children at Ysgol Henllan in Denbighshire are being
offered anti-viral treatment after one pupil was linked to the 1st
smallholding. The NPHS said 79 patients and staff from ward 6 at Glan
Clwyd Hospital were now being offered Tamiflu as a precaution. A
further 69 patients and staff from the A&E unit, Tryfan and Gogarth
wards at Ysbyty Gwynedd in Bangor have been contacted because a
patient, who has now been discharged, has also had treatment for the virus.

Marion Lyons, NPHS's communicable disease control consultant, said,
"We have assessed the risk to others and can confirm that the
healthcare worker was working at Ysbyty Glan Clwyd during the time
when she may have been infectious, between 21 and 23 May [2007]. The
patient at Ysbyty Gwynedd may also have been infectious while at
Ysbyty Gwynedd. However, as the patient was discharged on 18 May, and
the incubation period is 8 days, anyone would have had symptoms by 26 May."

The NPHS stressed that experience of this particular bird flu virus
in humans was limited, so it was "actively managing" the response.
Person-to-person spread would be very unusual, it said, but limited
spread has been seen elsewhere in the past. Dr Lyons added, "We are
looking for people who have had flu-like symptoms or conjunctivitis.
It is the symptoms which are important to identify. It is reassuring
that so few of the large number of contacts have had symptoms."

--
Communicated by:
ProMED-mail
<promed@promedmail.org>

******
[3]
Date: Tue 29 May 2007
Source: World Health Organisation (WHO, CSR, Disease Outbreak News,
Tue 29 May 2007 [edited]
<http://www.who.int/csr/don/2007_05_29/en/index.html>


Avian influenza A/(H7N2) in the United Kingdom
----------------------------------------------
On 25 May 2007, the United Kingdom Health Protection Agency (HPA)
announced that influenza A/H7N2 virus infection had been laboratory
confirmed in four individuals exposed to infected poultry in Corwen
Farm, Conwy, Wales. The poultry outbreak in Wales started on a
smallholding, Corwen Farm, Conwy, on 8 May 2007, was laboratory
confirmed on 24 May 2007, and notified to the World Organisation for
Animal Health on 25 May 2007.

For more information from the WHO Regional Office for Europe, see:
<http://www.euro.who.int/flu/situation/20070526_1 >
(Human cases of avian influenza A/H7N2 in the United Kingdom)

--
Communicated by:
ProMED-mail Rapporteur Marianne Hopp

[The number of individuals under surveillance and offered Tamiflu
treatment as a precautionary measure has increased, but the number of
persons exhibiting flu-like symptoms and/or conjunctivitis remains at
12. There is no unequivocal evidence to suggest that the H7N2 virus
exhibits an enhanced ability to spread from person to person. - Mod.CP]:tiphat:
http://www.promedmail.org/pls/prome..._BACK_PAGE,F2400_P1001_PUB_MAIL_ID:1000,37622
[see also:
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

No enhanced ability:rolleyes:
 
Re: Confirmation of Avian Influenza H7N2 Infection

Re: Confirmation of Avian Influenza H7N2 Infection

Patients given flu drugs after health worker contracts virus <TABLE cellSpacing=0 cellPadding=0 width="100%" border=0><TBODY></TBODY></TABLE><TABLE class=headerTable cellSpacing=0 cellPadding=0 width=* border=0><TBODY><TR><TD>May 30 2007

</TD></TR><TR><TD>
</TD></TR><TR><TD colSpan=2>by Madeleine Brindley, Western Mail
</TD></TR></TD></TR></TBODY></TABLE><TABLE cellSpacing=0 cellPadding=0 width=400 border=0><TBODY><TR><TD colSpan=3> </TD></TR><TR><TD colSpan=3>MORE than 70 patients and hospital staff have been given anti-flu drugs after a healthcare worker contracted the avian flu virus.
Staff and patients at two hospitals ? Ysbyty Glan Clwyd and Ysbyty Gwynedd ? have been identified as potentially at risk of contracting H7N2.
They are among a list of 221 people who have been identified as contacts, although the number of people confirmed as showing signs of contamination remains unchanged at 12 ? none are seriously ill.
It emerged last night that 79 patients and staff from ward six at Ysbyty Glan Clwyd have been offered Tamiflu as a precaution after coming into contact with a healthcare worker who is being treated for the virus.
And a further 69 patients and staff who were treated at Ysbyty Gwynedd?s accident and emergency department, Trysfan and Gogarth wards, have also been contacted by health officials.

Story continues
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A male patient was treated at the hospital in Bangor for the avian flu virus, but was discharged on May 18.

A spokesman for North West Wales NHS Trust, which runs the hospital, last night said 66 of these people had been contacted and none are experiencing symptoms.

He added, ?The incubation dates suggest that we will not see any further development of the disease in these people.?

The incubation period for this strain of avian flu is eight days, during which time infected people would be expected to experience flu-like symptoms or conjunctivitis.

Dr Marion Lyons, lead consultant in communicable diseases for the National Public Health Service for Wales (NPHS), said, ?We are actively managing the outbreak. This involves taking every precaution in identifying possible contacts of the infected poultry or people who have been ill after contact with the infected poultry.

?We have assessed the risk to others and can confirm that the healthcare worker was working at Ysbyty Glan Clwyd during the time when she may, possibly, have been infectious, between May 21 and May 23.

?Consequently the patients and staff with whom the healthcare worker has had contact are being offered Tamiflu as a precaution.?

Health officials have not yet been able to rule out person-to-person spread of avian flu, although it is understood that the majority of confirmed cases had some form of close contact with the smallholding at the centre of the outbreak.

It was confirmed last Thursday that 15 chickens had died from H7N2 avian flu at a farm in Llanfihangel Glyn Myfyr, near Corwen.

The chickens ? 22-week-old Rhode Island Reds ? had been bought by the smallholding?s owners Barbara Cowling and Tony Williams from Chelford Market, in Cheshire.

A 1km exclusion zone, to prevent the movement of birds, is in place around the farm and 30 birds were slaughtered last week.

Tests on samples taken from a second farm, on the Llyn Peninsula, last night confirmed birds at the site had not been infected with the virus despite a link with Chelford Market.

Meanwhile a dozen schoolchildren and two members of staff at Ysgol Henllan primary school, in Denbigh, have also been offered courses of Tamiflu after one of the pupils contracted the virus.

The child lives at a neighbouring property to the farm and the staff and pupils receiving treatment had all been in close proximity to the youngster.

Although health officials have been keen to reassure the public that the North Wales outbreak does not pose a serious risk to the public, the fact that a cluster of 12 people with symptoms has developed is unique.

Until now there have only been two occasions when the H7N2 avian flu virus crossed the species barrier from poultry to humans.

Both cases occurred in the US and involved only one person each ? in 2002 and 2003.

The North Wales outbreak will become the focus for intense scientific study, particularly if person-to-person transmission is established. Some of the 12 people who have been identified as experiencing flu-like symptoms and conjunctivitis did not have close contact with the infected poultry.

Dr Brendan Mason, a consultant epidemiologist at the NPHS, said, ?We are not, at the moment, saying that person-to-person transmission has taken place, but we cannot rule that out.

?We have been looking very hard to identify cases when they have occurred and to prevent them. We have been looking at people who have been in close contact with the poultry or with the human cases.

?This is not serious in the sense that we have had a limited number of cases and the cases of avian flu in humans have been very tight and associated with the small holding, with the chickens or people close to it. There is no suggestion that the virus has taken hold or that there are long chains of transmission from person to person to person.?

Many experts believe the next pandemic flu strain will emerge from the animal kingdom ? some believe the highly pathogenic H5N1 strain, which has killed more than 180 people across South East Asia could be a potential source, if it mutates to become more readily transmitted between humans. But the NPHS does not believe H7N2 will mutate to form a new, virulent virus.

Dr Mason said, ?We have been very fortunate in the timing of this because, where pandemic strains have emerged in the past, it has been through a reassortment of two viruses, where one person or an animal has become infected with two different strains with the ability to mix.

?We are well out of the European and UK flu season and no human flu virus strains are circulating in Wales at the moment.?
</TD></TR></TBODY></TABLE>

http://icwales.icnetwork.co.uk/0100...objectid=19216784&siteid=50082-name_page.html
 
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