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Contribution of systematic RT-PCR screening for influenza during the epidemic season

tetano

Editor, Senior Moderator
Med Mal Infect. 2014 Mar 4. pii: S0399-077X(14)00025-0. doi: 10.1016/j.medmal.2014.01.011. [Epub ahead of print]
Contribution of systematic RT-PCR screening for influenza during the epidemic season.
Martinot M1, Heller R2, Martin A3, Sagot E3, Souply L2, Mothes A3, Mohseni-Zadeh M3, de Briel D2.
Author information
Abstract
OBJECTIVE:

We assessed the systematic RT-PCR screening of patients admitted to an infectious diseases department (IDD), during the 2012-2013 influenza outbreak.
METHODOLOGY:

Patients admitted with cough and fever underwent a nasopharyngeal smear for RT-PCR screening.
RESULTS:

Ninety-eight patients were admitted in the IDD, from January 1st to February 22nd, 46 were screened; 11 male and 6 female patients (17.3%, mean age of 68 years) were positive. The diagnoses made in the emergency department, before RT-PCR screening, were most frequently lung infection and sepsis, but influenza in only 4 cases. The diagnosis of influenza led to stopping antibiotics (n=4), initiating curative (n=4) and preventive (n=4) treatments with oseltamivir, and isolating patients to prevent a hospital outbreak.
CONCLUSION:

Systematic RT-PCR screening allows a rapid therapeutic management and the prevention of hospital epidemic through appropriate isolation measures.

Copyright ? 2014 Elsevier Masson SAS. All rights reserved.
KEYWORDS:

D?pistage, Grippe, Influenza, PCR, Screening

PMID:
24612505
[PubMed - as supplied by publisher]

http://www.ncbi.nlm.nih.gov/pubmed/24612505
 
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