tetano
Editor, Senior Moderator
Annu Rev Immunol. 2013 Jan 3. [Epub ahead of print]
Control of Human Viral Infections by Natural Killer Cells.
Jost S, Altfeld M.
Source
Ragon Institute of MGH, MIT, and Harvard, Boston, MA 02129; email: sjost@partners.org.
Abstract
Natural killer (NK) cells are effector cells of the innate immune system and are important in the control of viral infection. Their relevance is reflected by the multiple mechanisms evolved by viruses to evade NK cell-mediated immune responses. Over recent years, our understanding of the interplay between NK cell immunity and viral pathogenesis has improved significantly. Here, we review the role of NK cells in the control of four important viral infections in humans: cytomegalovirus, influenza virus, HIV-1, and hepatitis C virus. Expected final online publication date for the Annual Review of Immunology Volume 31 is March 19, 2013. Please see http://www.annualreviews.org/catalog/pubdates.aspx for revised estimates.
PMID:
23298212
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23298212
Control of Human Viral Infections by Natural Killer Cells.
Jost S, Altfeld M.
Source
Ragon Institute of MGH, MIT, and Harvard, Boston, MA 02129; email: sjost@partners.org.
Abstract
Natural killer (NK) cells are effector cells of the innate immune system and are important in the control of viral infection. Their relevance is reflected by the multiple mechanisms evolved by viruses to evade NK cell-mediated immune responses. Over recent years, our understanding of the interplay between NK cell immunity and viral pathogenesis has improved significantly. Here, we review the role of NK cells in the control of four important viral infections in humans: cytomegalovirus, influenza virus, HIV-1, and hepatitis C virus. Expected final online publication date for the Annual Review of Immunology Volume 31 is March 19, 2013. Please see http://www.annualreviews.org/catalog/pubdates.aspx for revised estimates.
PMID:
23298212
[PubMed - as supplied by publisher]
http://www.ncbi.nlm.nih.gov/pubmed/23298212