tetano
Editor, Senior Moderator
J Clin Microbiol. 2019 May 29. pii: JCM.00373-19. doi: 10.1128/JCM.00373-19. [Epub ahead of print]
[h=1]Cost-Effective Respiratory Virus Testing.[/h] Pinsky BA[SUP]1[/SUP], Hayden RT[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] The timely and accurate diagnosis of respiratory virus infections has the potential to optimize downstream (post-testing) use of limited healthcare resources, including antibiotics, antivirals, ancillary testing, and inpatient and emergency room beds. Cost-effective algorithms for respiratory virus testing must take into consideration numerous factors, including which patients should be tested, what testing should be performed (for example, antigen versus RT-PCR, or influenza A/B versus a comprehensive respiratory virus panel), and the turnaround time necessary to achieve the desired post-testing outcomes. Despite the clinical impact of respiratory virus infections, the cost-effectiveness of respiratory virus testing is incompletely understood. In this manuscript, we review the literature pertaining to the cost-effectiveness of respiratory virus testing in pediatric and adult patient populations, and in emergency department, outpatient, and inpatient clinical settings. Furthermore, we consider the cost-effectiveness of a variety of testing methods, including rapid antigen, direct fluorescent antibody (DFA), and nucleic acid amplification tests (NAATs).
Copyright ? 2019 Pinsky and Hayden.
PMID: 31142607 DOI: 10.1128/JCM.00373-19
[h=1]Cost-Effective Respiratory Virus Testing.[/h] Pinsky BA[SUP]1[/SUP], Hayden RT[SUP]2[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] The timely and accurate diagnosis of respiratory virus infections has the potential to optimize downstream (post-testing) use of limited healthcare resources, including antibiotics, antivirals, ancillary testing, and inpatient and emergency room beds. Cost-effective algorithms for respiratory virus testing must take into consideration numerous factors, including which patients should be tested, what testing should be performed (for example, antigen versus RT-PCR, or influenza A/B versus a comprehensive respiratory virus panel), and the turnaround time necessary to achieve the desired post-testing outcomes. Despite the clinical impact of respiratory virus infections, the cost-effectiveness of respiratory virus testing is incompletely understood. In this manuscript, we review the literature pertaining to the cost-effectiveness of respiratory virus testing in pediatric and adult patient populations, and in emergency department, outpatient, and inpatient clinical settings. Furthermore, we consider the cost-effectiveness of a variety of testing methods, including rapid antigen, direct fluorescent antibody (DFA), and nucleic acid amplification tests (NAATs).
Copyright ? 2019 Pinsky and Hayden.
PMID: 31142607 DOI: 10.1128/JCM.00373-19