tetano
Editor, Senior Moderator
Eur J Public Health. 2019 May 5. pii: ckz074. doi: 10.1093/eurpub/ckz074. [Epub ahead of print]
[h=1]Cost-effectiveness of public health interventions against human influenza pandemics in France: a methodological contribution from the FLURESP European Commission project.[/h] Beresniak A[SUP]1,[/SUP][SUP]2[/SUP], Rizzo C[SUP]3[/SUP], Oxford J[SUP]4[/SUP], Goryński P[SUP]5[/SUP], Pistol A[SUP]6[/SUP], Fabiani M[SUP]3[/SUP], Napoli C[SUP]3[/SUP], Barral M[SUP]7[/SUP], Niddam L[SUP]8[/SUP], Bounekkar A[SUP]9[/SUP], Bonnevay S[SUP]9[/SUP], Lionis C[SUP]10[/SUP], Gauci C[SUP]11[/SUP], Bremond D[SUP]12,[/SUP][SUP]13[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] The FLURESP project is a public health project funded by the European Commission with the objective to design a methodological approach in order to compare the cost-effectiveness of existing public health measures against human influenza pandemics in four target countries: France, Italy, Poland and Romania. This article presents the results relevant to the French health system using a data set specifically collected for this purpose.
[h=4]METHODS:[/h] Eighteen public health interventions against human influenza pandemics were selected. Additionally, two public-health criteria were considered: 'achieving mortality reduction ≥40%' and 'achieving morbidity reduction ≥30%'. Costs and effectiveness data sources include existing reports, publications and expert opinions. Cost distributions were taken into account using a uniform distribution, according to the French health system.
[h=4]RESULTS:[/h] Using reduction of mortality as an effectiveness criterion, the most cost-effective options was 'implementation of new equipment of Extracorporeal membrane oxygenation (ECMO) equipment'. Targeting vaccination to health professionals appeared more cost-effective than vaccination programs targeting at risk populations. Concerning antiviral distribution programs, curative programs appeared more cost-effective than preventive programs. Using reduction of morbidity as effectiveness criterion, the most cost-effective option was 'implementation of new equipment ECMO'. Vaccination programs targeting the general population appeared more cost-effective than both vaccination programs of health professionals or at-risk populations. Curative antiviral programs appeared more cost-effective than preventive distribution programs, whatever the pandemic scenario.
[h=4]CONCLUSION:[/h] Intervention strategies against human influenza pandemics impose a substantial economic burden, suggesting a need to develop public-health cost-effectiveness assessments across countries.
? The Author(s) 2019. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.
PMID: 31056657 DOI: 10.1093/eurpub/ckz074
[h=1]Cost-effectiveness of public health interventions against human influenza pandemics in France: a methodological contribution from the FLURESP European Commission project.[/h] Beresniak A[SUP]1,[/SUP][SUP]2[/SUP], Rizzo C[SUP]3[/SUP], Oxford J[SUP]4[/SUP], Goryński P[SUP]5[/SUP], Pistol A[SUP]6[/SUP], Fabiani M[SUP]3[/SUP], Napoli C[SUP]3[/SUP], Barral M[SUP]7[/SUP], Niddam L[SUP]8[/SUP], Bounekkar A[SUP]9[/SUP], Bonnevay S[SUP]9[/SUP], Lionis C[SUP]10[/SUP], Gauci C[SUP]11[/SUP], Bremond D[SUP]12,[/SUP][SUP]13[/SUP].
[h=3]Author information[/h]
[h=3]Abstract[/h] [h=4]BACKGROUND:[/h] The FLURESP project is a public health project funded by the European Commission with the objective to design a methodological approach in order to compare the cost-effectiveness of existing public health measures against human influenza pandemics in four target countries: France, Italy, Poland and Romania. This article presents the results relevant to the French health system using a data set specifically collected for this purpose.
[h=4]METHODS:[/h] Eighteen public health interventions against human influenza pandemics were selected. Additionally, two public-health criteria were considered: 'achieving mortality reduction ≥40%' and 'achieving morbidity reduction ≥30%'. Costs and effectiveness data sources include existing reports, publications and expert opinions. Cost distributions were taken into account using a uniform distribution, according to the French health system.
[h=4]RESULTS:[/h] Using reduction of mortality as an effectiveness criterion, the most cost-effective options was 'implementation of new equipment of Extracorporeal membrane oxygenation (ECMO) equipment'. Targeting vaccination to health professionals appeared more cost-effective than vaccination programs targeting at risk populations. Concerning antiviral distribution programs, curative programs appeared more cost-effective than preventive programs. Using reduction of morbidity as effectiveness criterion, the most cost-effective option was 'implementation of new equipment ECMO'. Vaccination programs targeting the general population appeared more cost-effective than both vaccination programs of health professionals or at-risk populations. Curative antiviral programs appeared more cost-effective than preventive distribution programs, whatever the pandemic scenario.
[h=4]CONCLUSION:[/h] Intervention strategies against human influenza pandemics impose a substantial economic burden, suggesting a need to develop public-health cost-effectiveness assessments across countries.
? The Author(s) 2019. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.
PMID: 31056657 DOI: 10.1093/eurpub/ckz074